SCHEMBL8620692

SCHEMBL8620692

C1=CC2Nc3ccccc3NC2C=C1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 5/20 0.37
BRPF1 P55201 1/20 0.37
MAOA P21397 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
GAA P10253 2/20 0.35
MAPT P10636 2/20 0.35
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
GFER P55789 1/20 0.35
BRD4 O60885 4/20 0.33
IDO1 P14902 1/20 0.33
EP300 Q09472 1/20 0.33
NPC1 O15118 1/20 0.31
TNKS2 Q9H2K2 2/20 0.31
PBRM1 Q86U86 1/20 0.31
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL454276 0.77 HSPA1A (0.38) MAOAMEN1KMT2AGAAMAPT
SCHEMBL15704498 0.77 HSPA1A (0.38) MAOAMEN1KMT2AGAAMAPT
SCHEMBL19004692 0.77 HSPA1A (0.38) MAOAMEN1KMT2AGAAMAPT
SCHEMBL18237224 0.75
SCHEMBL17275114 0.74 GAA (0.31) GAAMAPT
SCHEMBL172197 0.73 PARP1 (0.36) CREBBPMEN1KMT2AGAAMAPT
SCHEMBL172220 0.73 MAOA (0.61) CREBBPMAOAMEN1KMT2AGAA
SCHEMBL2024487 0.73 MAPT (0.43) CREBBPMEN1KMT2AGAAMAPT
SCHEMBL10080214 0.73 TSHR (0.41) MAOAMEN1KMT2AGAATNKS2
SCHEMBL12333958 0.73 TNKS2 (0.37) KMT2AIDO1NPC1TNKS2PBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250338712-A1 LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2025-10-30 US claimed
US-20250338712-A1 LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO LTD (KR) 2025-10-30 US disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
EP-3960744-A1 CYCLOALKANE-CONDENSED POLYCYCLIC AROMATIC COMPOUND Kwansei Gakuin Educational Foundation (JP) 2022-03-02 EP disclosed
US-20220037591-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-03 US disclosed
WO-2021230133-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2021-11-18 WO disclosed
US-11136341-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2021-10-05 US disclosed
US-20210277056-A1 COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACID LINKED DOLASTATIN DERIVATIVES AMBRX, INC. (US) 2021-09-09 US disclosed
WO-2021114362-A1 HOLE TRANSPORT MATERIAL AND METHOD FOR PREPARATION THEREOF AND APPLICATION THEREOF 北京大学深圳研究生院 2021-06-17 WO disclosed
WO-2020250700-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2020-12-17 WO disclosed
WO-2020218079-A1 CYCLOALKANE-CONDENSED POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2020-10-29 WO disclosed
US-20200190116-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-06-18 US disclosed
US-20200190115-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-06-18 US disclosed
EP-3626722-A1 POLYCYCLIC AROMATIC COMPOUND Kwansei Gakuin Educational Foundation (JP) 2020-03-25 EP disclosed
EP-3150579-A1 FLUORANTHENE DERIVATIVE, ELECTRONIC DEVICE CONTAINING SAME, LIGHT-EMITTING ELEMENT, AND PHOTOELECTRIC CONVERSION ELEMENT Toray Industries, Inc. (JP) 2017-04-05 EP disclosed
US-20150080559-A1 Compositions Containing, Methods Involving, and Uses of Non-Natural Amino Acid Linked Dolastatin Derivatives AMBRX, INC. (US) 2015-03-19 US disclosed
CN-1078208-C Pyrrolyl tetrahydrobenzoquinoxaline diones, their preparation and use as glutamate receptor antagonists BASF AG (DE) 2002-01-23 CN disclosed
US-5849744-A Pyrrolyl tetrahydrobenzoquinoxaline diones, their preparation and use as glutamate receptor antagonist BASF AKTIENGESELLSCHAFT (DE) 1998-12-15 US disclosed
CN-1160400-A Pyrrolyl tetrahydrobenzoquinoxalinediones, their preparation and their use as glutamate receptor antagonists BASF AG (DE) 1997-09-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 CREBBP 4006/4885BRPF1 1635/4885MAOA 1283/4885
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR CREBBP 3641/4885BRPF1 1811/4885MAOA 115/4885
US-20200190116-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION TYR, NOD2, AHR CREBBP 4847/4885BRPF1 3060/4885MAOA 26/4885
US-11136341-B2 Polycyclic aromatic compound and light emission layer-forming composition TYR, NOD2, AHR CREBBP 4847/4885BRPF1 3060/4885MAOA 26/4885
US-20210277056-A1 COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACID LINKED DOLASTATIN DERIVATIVES DDOST, DAD1, PTMS CREBBP 4299/4885BRPF1 2375/4885MAOA 1539/4885
US-20200190115-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, ELOC CREBBP 2082/4885BRPF1 832/4885MAOA 2073/4885
US-20220037591-A1 Polycyclic aromatic compound F11, C1R, RNF31 CREBBP 4006/4885BRPF1 1635/4885MAOA 1283/4885
US-20150080559-A1 Compositions Containing, Methods Involving, and Uses of Non-Natural Amino Acid Linked Dolastatin Derivatives DDOST, DAD1, PTMS CREBBP 4312/4885BRPF1 2396/4885MAOA 1553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.