Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049329 | 0.78 | ALDH1A1 (0.46) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL8244836 | 0.77 | CYP2D6 (0.49) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL4456470 | 0.77 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL8935650 | 0.74 | ALDH1A1 (0.43) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL9575973 | 0.74 | CYP2D6 (0.54) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL24227193 | 0.72 | TRPA1 (0.46) | CYP2D6 | |
| SCHEMBL18230821 | 0.71 | PKM (0.49) | ALDH1A1MAPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL8970225 | 0.70 | FFAR1 (0.49) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL9575627 | 0.70 | MAPT (0.47) | ALDH1A1POLBMAPTUSP2CACNA1B | |
| SCHEMBL16805853 | 0.69 | NPC1 (0.41) | ALDH1A1POLBMAPTUSP2CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216336-B1 | PROCESS FOR PRODUCTION OF CYCLIC POLYORGANOSILOXANE, CURING AGENT, CURABLE COMPOSITION, AND CURED PRODUCT OF THE CURABLE COMPOSITION | KANEKA CORP (JP) | 2015-11-04 | — | — | EP | disclosed |