Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049329 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTPOLBUSP2CACNA1B | |
| SCHEMBL4456470 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBUSP2CACNA1B | |
| SCHEMBL17226151 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTPOLBUSP2CACNA1B | |
| SCHEMBL9575627 | 0.72 | MAPT (0.47) | ALDH1A1MAPTPOLBUSP2CACNA1B | |
| SCHEMBL5611799 | 0.71 | MAPT (0.46) | ALDH1A1MAPTPOLBUSP2CACNA1B | |
| 1,4-Diallyloxybenzene SCHEMBL302448 | 0.71 | CA12 (0.63) | ALDH1A1MAPTPOLBUSP2CACNA1B | |
| SCHEMBL15096036 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MAPTPOLBUSP2CACNA1B | |
| SCHEMBL1652185 | 0.70 | CA12 (0.50) | ALDH1A1MAPTPOLBUSP2CACNA1B | |
| SCHEMBL7929787 | 0.70 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBUSP2CACNA1B | |
| SCHEMBL8419864 | 0.70 | FFAR1 (0.46) | ALDH1A1MAPTPOLBUSP2CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589586-A | Nucleosides attached to a solid support through a 3'-silyl linkage and their use in oligonucleotide synthesis | PHARMACIA LKB BIOTECHNOLOGY AB (SE) | 1996-12-31 | — | — | US | disclosed |
| EP-0514513-B1 | METHOD AND MEANS FOR OLIGONUCLEOTIDE SYNTHESIS | PHARMACIA BIOTECH AB (SE) | 1996-01-31 | — | — | EP | disclosed |
| EP-0514513-A1 | METHOD AND MEANS FOR OLIGONUCLEOTIDE SYNTHESIS. | PHARMACIA LKB BIOTECH (SE) | 1992-11-25 | — | — | EP | disclosed |
| WO-1992009615-A1 | METHOD AND MEANS FOR OLIGONUCLEOTIDE SYNTHESIS | PHARMACIA LKB BIOTECHNOLOGY AB (SE) | 1992-06-11 | — | — | WO | disclosed |