SCHEMBL172262

SCHEMBL172262

CCCNC1CCc2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.64
MAOB P27338 4/20 0.64
ACHE P22303 2/20 0.64
BCHE P06276 1/20 0.64
ADRA2B P18089 1/20 0.64
ADRA2C P18825 1/20 0.64
ADRA1A P35348 1/20 0.64
HTR6 P50406 1/20 0.64
PDPK1 O15530 1/20 0.61
HTR1A P08908 1/20 0.56
HTT P42858 1/20 0.52
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
KDM1A O60341 2/20 0.47
SIGMAR1 Q99720 1/20 0.46
DRD2 P14416 1/20 0.45
SLC18A3 Q16572 1/20 0.45
FADS1 O60427 1/20 0.44
EPHX2 P34913 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13911216 1.00 MAOA (0.64) MAOAMAOBACHEBCHEADRA2B
SCHEMBL19289840 0.90 HTT (0.64) MAOAMAOBACHEBCHEADRA2B
SCHEMBL62691 0.90 HTT (0.64) MAOAMAOBACHEBCHEADRA2B
SCHEMBL62692 0.90 HTT (0.64) MAOAMAOBACHEBCHEADRA2B
SCHEMBL172566 0.90 MAOA (0.60) MAOAMAOBACHEBCHEADRA2B
SCHEMBL6923878 0.89 MAOA (0.59) MAOAMAOBACHEBCHEADRA2B
SCHEMBL6851081 0.86 MAOA (0.68) MAOAMAOBACHEBCHEADRA2B
SCHEMBL10282640 0.86 MAOA (0.68) MAOAMAOBACHEBCHEADRA2B
SCHEMBL6851796 0.86 MAOA (0.68) MAOAMAOBACHEBCHEADRA2B
SCHEMBL18995764 0.83 MAOA (0.59) MAOAMAOBACHEBCHEADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260027148-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS BEXSON BIOMEDICAL INC (US) 2026-01-29 US disclosed
US-20260014191-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS BEXSON BIOMEDICAL INC (US) 2026-01-15 US disclosed
US-20260014190-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS BEXSON BIOMEDICAL INC (US) 2026-01-15 US disclosed
US-12472201-B2 Complexing agent salt formulations of pharmaceutical compounds BEXSON BIOMEDICAL, INC. (US) 2025-11-18 US disclosed
EP-4079311-B1 NMN AND DERIVATIVES FOR USE IN THE TREATMENT OF DEPRESSION AND/OR ANXIETY IN PATIENTS HAVING A FORM OF PARKINSONISM NUVAMID SA (CH) 2025-10-01 EP disclosed
US-20240417421-A1 NMN And Derivatives For Its Use In The Treatment Of Depression And/Or Anxiety In Patients Having A Form Of Parkinsonism NUVAMID SA (CH) 2024-12-19 US disclosed
US-20240116971-A1 NMN AND DERIVATIVES FOR ITS USE IN THE TREATMENT OF DEPRESSION AND/OR ANXIETY IN PATIENTS HAVING A FORM OF PARKINSONISM NUVAMID SA (CH) 2024-04-11 US disclosed
WO-2024020572-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PTSD NEW YORK STEM CELL FOUNDATION, INC. (US) 2024-01-25 WO disclosed
US-20230124101-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS BEXSON BIOMEDICAL, INC. 2023-04-20 US disclosed
US-11534454-B2 Complexing agent salt formulations of pharmaceutical compounds BEXSON BIOMEDICAL, INC. (US) 2022-12-27 US disclosed
WO-2010059913-A2 PREPARATION OF RASAGILINE AND SALTS THEREOF DR. REDDY'S LABORATORIES LTD. (IN) 2010-05-27 WO disclosed
WO-2010059913-A2 PREPARATION OF RASAGILINE AND SALTS THEREOF DR. REDDY'S LABORATORIES LTD. (IN) 2010-05-27 WO disclosed
US-20070054892-A1 Isoquinoline potassium channel inhibitors MERCK SHARP & DOHME CORP. 2007-03-08 US disclosed
US-5668181-A INHIBITOR OF MONOAMINE OXIDASE TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 1997-09-16 US disclosed
US-5576353-A ADMINISTERING N-PROPARGYL-1-AMINOINDAN TO A SUBJECT TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 1996-11-19 US disclosed
US-5457133-A Treating Parkinson's disease, memory disorders, Alzheimer's disease, depression and hyperactive syndrome TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 1995-10-10 US disclosed
US-5453446-A Use of the R-enantiomers of N-propargyl 1-aminoindan compounds for treating Parkinson's disease. TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 1995-09-26 US disclosed
US-5387612-A Administering title compound or salt; memory disorders TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 1995-02-07 US disclosed
EP-0436492-B1 R-Enantiomer of N-propargyl-1-aminoindan, its preparation and pharmaceutical compositions containing it TEVA PHARMA (IL) 1994-06-08 EP disclosed
EP-0436492-A2 R-Enantiomer of N-propargyl-1-aminoindan, its preparation and pharmaceutical compositions containing it Teva Pharmaceutical Industries Limited (IL) 1991-07-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014191-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS SLC6A4, SLC6A3, SIGMAR1 MAOA 297/4885MAOB 405/4885ACHE 712/4885
US-20240116971-A1 NMN AND DERIVATIVES FOR ITS USE IN THE TREATMENT OF DEPRESSION AND/OR ANXIETY IN PATIENTS HAVING A FORM OF PARKINSONISM SNCA, NLN, PARK7 MAOA 47/4885MAOB 37/4885ACHE 89/4885
US-20260027148-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS SLC6A3, SIGMAR1, SLC6A4 MAOA 285/4885MAOB 463/4885ACHE 812/4885
US-11534454-B2 Complexing agent salt formulations of pharmaceutical compounds SLC10A1, SLC5A6, MC2R MAOA 1806/4885MAOB 2001/4885ACHE 2246/4885
US-20230124101-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS SLC10A1, SLC5A6, MC2R MAOA 1806/4885MAOB 2001/4885ACHE 2246/4885
US-20240417421-A1 NMN And Derivatives For Its Use In The Treatment Of Depression And/Or Anxiety In Patients Having A Form Of Parkinsonism SNCA, NLN, PARK7 MAOA 64/4885MAOB 57/4885ACHE 117/4885
US-20070054892-A1 Isoquinoline potassium channel inhibitors KCNQ1, KCNQ2, KCNQ5 MAOA 2930/4885MAOB 2879/4885ACHE 1931/4885
US-12472201-B2 Complexing agent salt formulations of pharmaceutical compounds SLC10A1, SLC5A6, MC2R MAOA 1806/4885MAOB 2001/4885ACHE 2246/4885
US-20260014190-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS SIGMAR1, OPRK1, SLC6A2 MAOA 171/4885MAOB 283/4885ACHE 1538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.