Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145157 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4ETSHRMCHR1KMT2A | |
| SCHEMBL6869567 | 0.67 | CYP19A1 (0.39) | ALDH1A1DRD2DRD3 | |
| SCHEMBL21799751 | 0.65 | ANPEP (0.50) | ALDH1A1 | |
| SCHEMBL4152298 | 0.65 | OPRD1 (0.40) | BDKRB1 | |
| SCHEMBL172730 | 0.65 | DNM1 (0.49) | ALDH1A1KDM4EHPGD | |
| SCHEMBL14847248 | 0.64 | KDM4E (0.56) | ALDH1A1KDM4ETSHRMCHR1KMT2A | |
| SCHEMBL13039461 | 0.64 | ALDH1A1 (0.59) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL14847238 | 0.64 | ALDH1A1 (0.59) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL38653550 | 0.64 | DRD2 (0.57) | ALDH1A1DRD2DRD3KMT2AMEN1 | |
| SCHEMBL21799963 | 0.64 | ADRB2 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |