Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128266 | 0.81 | MTNR1A (0.47) | MTNR1AMTNR1B | |
| SCHEMBL127375 | 0.76 | MTNR1B (0.43) | MTNR1AMTNR1B | |
| SCHEMBL172456 | 0.73 | MTNR1B (0.60) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL124106 | 0.72 | MTNR1A (0.67) | MTNR1AMTNR1B | |
| SCHEMBL125199 | 0.71 | MTNR1A (0.41) | MTNR1AMTNR1B | |
| SCHEMBL127156 | 0.70 | MTNR1B (0.68) | MTNR1AMTNR1B | |
| SCHEMBL125064 | 0.70 | MTNR1A (0.38) | MTNR1AMTNR1B | |
| SCHEMBL172150 | 0.70 | MTNR1B (0.63) | MTNR1AMTNR1B | |
| SCHEMBL172399 | 0.70 | MTNR1A (0.67) | MTNR1AMTNR1B | |
| SCHEMBL172381 | 0.70 | MTNR1B (0.62) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100895-B1 | TRICYCLIC COMPOUND AND MEDICAL USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2012-03-07 | — | — | EP | disclosed |