Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15870973 | 0.88 | MAPT (0.41) | MCL1WDR5MAPTALDH1A1GAA | |
| SCHEMBL17264194 | 0.84 | WDR5 (0.47) | WDR5MAPTALDH1A1HPGDL3MBTL1 | |
| SCHEMBL17264192 | 0.80 | GPR84 (0.41) | WDR5MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL17264195 | 0.79 | KCNJ11 (0.34) | MAPTALDH1A1GAATDP1POLB | |
| SCHEMBL17070768 | 0.75 | WDR5 (0.59) | WDR5MAPTALDH1A1TDP1HPGD | |
| SCHEMBL17255965 | 0.74 | MAPT (0.50) | WDR5MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL17264189 | 0.73 | WDR5 (0.49) | WDR5MAPTALDH1A1POLBHPGD | |
| SCHEMBL13351437 | 0.72 | SIGMAR1 (0.38) | L3MBTL1 | |
| SCHEMBL12299106 | 0.72 | SLC6A2 (0.38) | L3MBTL1 | |
| SCHEMBL13027951 | 0.72 | SIGMAR1 (0.38) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150329772-A1 | Materials for Electronic Devices | MERCK PATENT GMBH (DE) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329772-A1 | Materials for Electronic Devices | EFNA1, SDHB, ETFA | MCL1 4229/4885WDR5 4233/4885MAPT 2087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.