Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 7/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.45 |
| ▸ | GABRR1 | P24046 | 5/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.45 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.43 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13102074 | 0.78 | GABRA1 (0.40) | GABRA5GABRB2GABRA1GABRR1GABRA4 | |
| SCHEMBL9182927 | 0.74 | GABRA1 (0.45) | GABRA5GABRB2GABRA1GABRR1GABRA4 | |
| SCHEMBL11347906 | 0.68 | MAPT (0.41) | GABRA5GABRB2GABRA1GABRR1GABRA4 | |
| SCHEMBL9915348 | 0.67 | GABRA1 (0.38) | GABRA5GABRB2GABRA1GABRR1GABRA4 | |
| SCHEMBL20840785 | 0.65 | GABRA1 (0.43) | GABRA5GABRB2GABRA1GABRR1GABRA4 | |
| Hydrochloric Acid SCHEMBL6747817 | 0.65 | NAPRT (0.40) | GABRA5GABRB2GABRA1GABRR1GABRA4 | |
| SCHEMBL20195566 | 0.62 | — | — | |
| SCHEMBL10652835 | 0.62 | GABRA5 (0.50) | GABRA5GABRB2GABRA1GABRR1GABRA4 | |
| SCHEMBL18098014 | 0.61 | — | — | |
| SCHEMBL9054967 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9381200-B2 | Nitrogen containing compounds | WOCKHARDT LIMITED (IN) | 2016-07-05 | — | — | US | disclosed |
| US-20150328201-A1 | NITROGEN CONTAINING COMPOUNDS | WOCKHARDT LIMITED (IN) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150328201-A1 | NITROGEN CONTAINING COMPOUNDS | NOS2, NOS1, NCF1 | GABRA5 3343/4885GABRB2 2856/4885GABRA1 3348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.