Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.56 |
| ▸ | HTR2A | P28223 | 17/20 | 0.56 |
| ▸ | DRD3 | P35462 | 17/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3269252 | 0.84 | DRD2 (0.50) | DRD2HTR2ADRD3HTR2CSIRT2 | |
| SCHEMBL1728813 | 0.81 | SIRT2 (0.51) | DRD2HTR2CSIRT2SIRT1SIRT3 | |
| SCHEMBL15971750 | 0.79 | HTR2C (0.65) | DRD2HTR2ADRD3HTR2C | |
| SCHEMBL1727950 | 0.77 | SIRT2 (0.50) | SIRT2SIRT1SIRT3 | |
| SCHEMBL1727743 | 0.77 | SIRT2 (0.50) | SIRT2SIRT1SIRT3 | |
| SCHEMBL1730265 | 0.77 | SIRT2 (0.50) | SIRT2SIRT1SIRT3 | |
| SCHEMBL1730203 | 0.77 | CHRM4 (0.51) | SIRT2SIRT1SIRT3 | |
| SCHEMBL1730153 | 0.75 | CHRM4 (0.52) | DRD2SIRT2SIRT1SIRT3 | |
| SCHEMBL3269249 | 0.75 | HTR2C (0.47) | DRD2HTR2ADRD3HTR2C | |
| SCHEMBL1729130 | 0.75 | ENPP1 (0.51) | DRD2DRD3HTR2CSIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |