Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.34 |
| ▸ | PDE8B | O95263 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727913 | 0.82 | HRH3 (0.38) | GPR119AOC3 | |
| SCHEMBL1728058 | 0.81 | ALDH1A1 (0.42) | KDM4EDPP4DPP8DPP9DPP7 | |
| SCHEMBL1729204 | 0.81 | KDM4E (0.44) | GPR119KDM4EDPP4DPP8DPP9 | |
| SCHEMBL1727973 | 0.79 | HRH3 (0.44) | — | |
| SCHEMBL1730042 | 0.79 | HSD17B10 (0.44) | AOC3 | |
| SCHEMBL1730188 | 0.79 | AKR1C3 (0.39) | KDM4EDPP4DPP8DPP9DPP7 | |
| SCHEMBL1730161 | 0.79 | DEGS1 (0.43) | GPR119KDM4ESIGMAR1 | |
| SCHEMBL1728022 | 0.78 | FFAR4 (0.34) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL1729774 | 0.78 | LMNA (0.36) | KDM4EAOC3DPP4DPP8DPP9 | |
| SCHEMBL1729040 | 0.78 | HCAR2 (0.46) | KDM4EDPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |