Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727583 | 0.81 | GPR119 (0.38) | DPP4DPP8DPP9DPP7KDM4E | |
| SCHEMBL1729774 | 0.79 | LMNA (0.36) | ALDH1A1HPGDKMT2ANPC1RAB9A | |
| SCHEMBL1730312 | 0.79 | CRHBP (0.43) | ALDH1A1HPGDNPSR1KDM4EUSP2 | |
| SCHEMBL1728888 | 0.78 | KDM4E (0.42) | ALDH1A1HPGDNPSR1KMT2ANPC1 | |
| SCHEMBL1729389 | 0.77 | DPP4 (0.43) | DPP4DPP7 | |
| SCHEMBL1728022 | 0.77 | FFAR4 (0.34) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL1729204 | 0.77 | KDM4E (0.44) | ALDH1A1L3MBTL1DPP4DPP8DPP9 | |
| SCHEMBL1729040 | 0.77 | HCAR2 (0.46) | ALDH1A1HPGDNPSR1KMT2ANPC1 | |
| SCHEMBL1727903 | 0.77 | KMT2A (0.38) | ALDH1A1KMT2ADPP4OPRK1DPP8 | |
| SCHEMBL1730251 | 0.76 | DPP4 (0.42) | DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |