Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 5/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 4/20 | 0.37 |
| ▸ | NOS3 | P29474 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727643 | 0.90 | CNR1 (0.47) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1729806 | 0.88 | CNR1 (0.44) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1728853 | 0.88 | CNR1 (0.44) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1727691 | 0.88 | CNR1 (0.41) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1728079 | 0.86 | DRD2 (0.42) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1729843 | 0.82 | CNR1 (0.44) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1730286 | 0.82 | CNR1 (0.44) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1729147 | 0.82 | MGLL (0.43) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1727992 | 0.81 | CASR (0.41) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL1727718 | 0.79 | CNR1 (0.47) | HTR1ADRD2DRD4HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |