SCHEMBL17278704

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17278701	1.00	HDAC6 (0.46)	HDAC6MAOAP2RX4BCHEACHE
	SCHEMBL17278670	0.97	HDAC6 (0.44)	HDAC6MAOAP2RX4BCHEACHE
	SCHEMBL17278672	0.96	HDAC6 (0.43)	HDAC6MAOAP2RX4BCHEACHE
	SCHEMBL17278520	0.91	HDAC6 (0.40)	HDAC6P2RX4BCHEACHEMAPT
	SCHEMBL17279248	0.90	HDAC6 (0.39)	HDAC6LMNAMAPT
	SCHEMBL17278708	0.90	HDAC6 (0.39)	HDAC6MAOA
	SCHEMBL16271056	0.89	P2RX4 (0.39)	P2RX4MAPTL3MBTL1SMN1; SMN2
	SCHEMBL16449658	0.89	HDAC6 (0.54)	HDAC6MAOABCHEACHENOX1
	SCHEMBL31059182	0.89	P2RX4 (0.39)	P2RX4MAPTL3MBTL1SMN1; SMN2
	SCHEMBL17278506	0.88	HDAC6 (0.38)	HDAC6BCHENOX1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.