Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.45 |
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19978177 | 0.77 | BRD4 (0.56) | SMN1; SMN2MDM2BRD4 | |
| SCHEMBL11095660 | 0.74 | MDM2 (0.53) | SMN1; SMN2MDM2BRD4PDGFRAMAPK8 | |
| SCHEMBL19663896 | 0.73 | LMNA (0.50) | SMN1; SMN2MDM2BRD4PDGFRAMAPK8 | |
| SCHEMBL6381138 | 0.68 | SMN1; SMN2 (0.49) | SMN1; SMN2MDM2BRD4KDM4EHPGD | |
| SCHEMBL25693651 | 0.67 | SMN1; SMN2 (0.47) | SMN1; SMN2MDM2BRD4KDM4EHPGD | |
| SCHEMBL13621207 | 0.67 | SMN1; SMN2 (1.00) | SMN1; SMN2MDM2BRD4KDM4EALDH1A1 | |
| SCHEMBL10446054 | 0.65 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4EHPGDF2GAA | |
| SCHEMBL1260425 | 0.65 | CYP11B1 (0.66) | KDM4EF2ALDH1A1HSD17B10ESR1 | |
| SCHEMBL8798888 | 0.65 | KDM4E (0.51) | SMN1; SMN2KDM4EHPGDGAAPLA2G10 | |
| SCHEMBL9203392 | 0.64 | F2 (0.55) | SMN1; SMN2KDM4EHPGDF2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10012777-B2 | Resin composition | Konica Minolta, Inc. (JP) | 2018-07-03 | — | — | US | disclosed |
| US-10012777-B2 | Resin composition | Konica Minolta, Inc. (JP) | 2018-07-03 | — | — | US | disclosed |
| US-20150338563-A1 | RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE | KONICA MINOLTA, INC (JP) | 2015-11-26 | — | — | US | disclosed |
| US-20150338563-A1 | RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE | KONICA MINOLTA, INC (JP) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150338563-A1 | RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE | HRH3, HELZ, NBAS | SMN1; SMN2 4639/4885MDM2 920/4885BRD4 691/4885 |
| US-10012777-B2 | Resin composition | NBAS, WDR5, HRH3 | SMN1; SMN2 4379/4885MDM2 1050/4885BRD4 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.