SCHEMBL17280208

SCHEMBL17280208

CCOS(=O)(=O)c1ccccc1-c1nc(-c2cccc(-c3c[nH]c(-c4ccccc4S(=O)(=O)OCC)n3)c2)c[nH]1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 9/20 0.35
CYP3A4 P08684 8/20 0.35
CYP1A2 P05177 8/20 0.35
CYP2C19 P33261 8/20 0.35
CYP2D6 P10635 3/20 0.34
ALOX5AP P20292 3/20 0.32
FEN1 P39748 3/20 0.32
PDGFRB P09619 2/20 0.32
CCNT1 O60563 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31
CDK9 P50750 1/20 0.31
ATR Q13535 1/20 0.31
ALDH1A1 P00352 2/20 0.31
NPC1 O15118 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
LMNA P02545 1/20 0.31
HSP90AA1 P07900 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17280092 0.80 NR1H2 (0.44) CYP2C9CYP3A4CYP1A2CYP2C19CYP2D6
SCHEMBL17279944 0.78 ADORA3 (0.46) CYP3A4CYP1A2ALDH1A1NPC1MAPK1
SCHEMBL17280172 0.76 CCNT1 (0.43) ALOX5APFEN1PDGFRBCCNT1CCNA2
SCHEMBL17280202 0.73 KMT2A (0.43) CYP2C9CYP3A4CYP1A2CYP2C19ALOX5AP
SCHEMBL17280163 0.71 DCUN1D1 (0.44) ALDH1A1NPC1RAB9AHPGDNPSR1
SCHEMBL17280171 0.71 DCUN1D1 (0.46) ALDH1A1RAB9ALMNAHPGD
SCHEMBL17280177 0.71 DCUN1D1 (0.48) PDGFRBALDH1A1NPC1RAB9ALMNA
SCHEMBL17280190 0.68 CFD (0.41) CYP1A2ALDH1A1NPC1RAB9ATHRB
SCHEMBL29415266 0.68 GAA (0.39) CYP2C9ALDH1A1MAPK1LMNA
SCHEMBL778991 0.68 GAA (0.39) CYP2C9ALDH1A1MAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020149206-A1 METHOD FOR PRODUCING ACRYLIC RESIN FILM コニカミノルタ株式会社 2020-07-23 WO disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 US disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE HRH3, HELZ, NBAS CYP2C9 1773/4885CYP3A4 1050/4885CYP1A2 1631/4885
US-10012777-B2 Resin composition NBAS, WDR5, HRH3 CYP2C9 1915/4885CYP3A4 1193/4885CYP1A2 1695/4885
US-20180203175-A1 TRIAZOLE COMPOUND H1-10, TTI2, H1-2 CYP2C9 101/4885CYP3A4 18/4885CYP1A2 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.