Sugi Predict

Sugi Predict / Compounds / SCHEMBL17280202

SCHEMBL17280202

SCHEMBL17280202

CS(=O)(=O)c1ccccc1-c1c[nH]c(-c2cccc(-c3nc(-c4ccccc4S(C)(=O)=O)c[nH]3)c2)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ ALOX5AP P20292 3/20 0.40
▸ FEN1 P39748 3/20 0.40
▸ ATR Q13535 2/20 0.40
▸ ALOX5 P09917 1/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ KDM4E B2RXH2 2/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ POLB P06746 1/20 0.36
▸ GRM2 Q14416 1/20 0.36
▸ HSD11B1 P28845 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ LMNA P02545 2/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17280207 0.78 GRK6 (0.46) ATRALOX5GRM2NPBWR1
SCHEMBL17280162 0.78 IDO1 (0.40) KMT2ARAB9AMEN1KDM4EALDH1A1
SCHEMBL17280203 0.75 KDM4C (0.44) KMT2ARAB9AALOX5APFEN1MEN1
SCHEMBL17280179 0.74 CCNT1 (0.42) KMT2ARAB9AALOX5APFEN1ATR
SCHEMBL17279786 0.73 MEN1 (0.46) KMT2ARAB9AMEN1KDM4EALDH1A1
SCHEMBL17279953 0.73 ALOX15 (0.49) KMT2ARAB9AMEN1KDM4EALDH1A1
SCHEMBL8814144 0.73 POLB (0.44) KMT2ARAB9AALOX5APFEN1ATR
SCHEMBL17280208 0.73 CYP2C9 (0.35) RAB9AALOX5APFEN1ATRALDH1A1
SCHEMBL17280087 0.72 RAB9A (0.49) KMT2ARAB9AALOX5MEN1ALDH1A1
SCHEMBL17279780 0.71 MEN1 (0.43) KMT2ARAB9AMEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 — — US disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 — — US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 — — US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 — — US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 — — US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE HRH3, HELZ, NBAS KMT2A 3422/4885RAB9A 1803/4885ALOX5AP 2326/4885
US-10012777-B2 Resin composition NBAS, WDR5, HRH3 KMT2A 2680/4885RAB9A 2127/4885ALOX5AP 2067/4885
US-20180203175-A1 TRIAZOLE COMPOUND H1-10, TTI2, H1-2 KMT2A 1136/4885RAB9A 1962/4885ALOX5AP 3770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.