Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SCD | O00767 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727652 | 0.90 | SCD (0.42) | CHRNA7HTR3ACHRNB4CHRNA3NPC1 | |
| SCHEMBL1727912 | 0.85 | CNR1 (0.42) | — | |
| SCHEMBL1729166 | 0.84 | LMNA (0.39) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL1728046 | 0.83 | NPC1 (0.49) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL1730046 | 0.79 | DKK1 (0.49) | KDM4EALDH1A1TSHR | |
| SCHEMBL1729255 | 0.78 | HTR1A (0.43) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1728900 | 0.76 | PRKCQ (0.38) | HTR3AMEN1KMT2ATSHRNFKB1 | |
| SCHEMBL1727687 | 0.76 | PDE10A (0.43) | KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL1730318 | 0.76 | HRH3 (0.43) | KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL1728906 | 0.76 | DEGS1 (0.48) | KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |