Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 8/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 8/20 | 0.41 |
| ▸ | ITGAL | P20701 | 8/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 3/20 | 0.39 |
| ▸ | SKP1 | P63208 | 3/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727745 | 0.87 | RXRA (0.46) | RXRAITGB2ICAM1ITGALCHRM4 | |
| SCHEMBL1728015 | 0.84 | FFAR4 (0.52) | OPRD1CHRM4USP30 | |
| SCHEMBL1727572 | 0.83 | CNR1 (0.41) | AOC3CKS1BSKP1SKP2 | |
| SCHEMBL1730249 | 0.83 | HTR3A (0.42) | AOC3CHRM4CKS1BSKP1SKP2 | |
| SCHEMBL1727652 | 0.81 | SCD (0.42) | — | |
| SCHEMBL1729202 | 0.80 | KDM4E (0.46) | — | |
| SCHEMBL1729231 | 0.80 | KDM4E (0.40) | AOC3CHRM4MCHR1 | |
| SCHEMBL1729037 | 0.79 | HCAR2 (0.46) | CKS1BSKP1SKP2 | |
| SCHEMBL1729384 | 0.79 | DPP4 (0.44) | — | |
| SCHEMBL1727953 | 0.78 | PDE10A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |