Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729017 | 0.90 | DRD3 (0.42) | AOC3DRD4HTR1AHTR2ASLC6A4 | |
| SCHEMBL1730270 | 0.90 | EGLN1 (0.47) | AOC3DRD4HTR1AHTR2ASLC6A4 | |
| SCHEMBL1729203 | 0.89 | GRIN1 (0.42) | SLC6A7AOC3GRIN1GRIN2BDRD4 | |
| SCHEMBL1727992 | 0.85 | CASR (0.41) | SLC6A7DRD4HTR1AHTR2ADRD3 | |
| SCHEMBL1727880 | 0.85 | CNR2 (0.50) | SLC6A7AOC3DRD4HTR1AHTR2A | |
| SCHEMBL1730237 | 0.83 | MCHR1 (0.44) | SLC6A7AOC3DRD4HTR1AHTR2A | |
| SCHEMBL1728735 | 0.81 | DRD4 (0.49) | SLC6A7GRIN1GRIN2BDRD4HTR1A | |
| SCHEMBL1727895 | 0.81 | EGLN1 (0.43) | AOC3DRD4HTR1AHTR2ASLC6A4 | |
| SCHEMBL1728079 | 0.80 | DRD2 (0.42) | AOC3DRD4HTR1AHTR2ADRD3 | |
| SCHEMBL1729147 | 0.80 | MGLL (0.43) | AOC3DRD4HTR1AHTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |