Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729843 | 0.91 | CNR1 (0.44) | CNR1HTR1AHTR2AHTR2CHTR7 | |
| SCHEMBL1727866 | 0.88 | CNR1 (0.44) | CNR1HTR1AHTR2AHTR2CHTR7 | |
| SCHEMBL1728979 | 0.88 | HTR1A (0.43) | CNR1HTR1AHTR2AHTR2CHTR7 | |
| SCHEMBL1729806 | 0.85 | CNR1 (0.44) | CNR1HTR1AHTR2AHTR2CHTR7 | |
| SCHEMBL1728079 | 0.84 | DRD2 (0.42) | HTR1AHTR2AHTR2CHTR7DRD2 | |
| SCHEMBL1729278 | 0.83 | HTR1A (0.41) | CNR1HTR1AHTR2AHTR7DRD4 | |
| SCHEMBL1727643 | 0.82 | CNR1 (0.47) | CNR1HTR1AHTR2AHTR2CHTR7 | |
| SCHEMBL1730286 | 0.80 | CNR1 (0.44) | CNR1HTR1AHTR2AHTR2CHTR7 | |
| SCHEMBL1728845 | 0.80 | CNR1 (0.45) | CNR1HTR1AHTR2AHTR2CHTR7 | |
| SCHEMBL1730237 | 0.79 | MCHR1 (0.44) | HTR1AHTR2ADRD4DRD3CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |