Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729278 | 0.90 | HTR1A (0.41) | AOC3AURKAAURKBHRH1RET | |
| SCHEMBL1728914 | 0.89 | MCHR1 (0.44) | MCHR1HRH2HRH1RETSLC6A4 | |
| SCHEMBL1727880 | 0.86 | CNR2 (0.50) | AOC3AURKAAURKBHRH2HRH1 | |
| SCHEMBL1729843 | 0.85 | CNR1 (0.44) | MCHR1HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL1730270 | 0.84 | EGLN1 (0.47) | AOC3AURKAAURKBRETSLC6A4 | |
| SCHEMBL1728819 | 0.83 | SLC6A7 (0.43) | AOC3AURKAAURKBSLC6A4HTR1A | |
| SCHEMBL1729147 | 0.81 | MGLL (0.43) | AOC3AURKAAURKBSLC6A4HTR1A | |
| SCHEMBL1727411 | 0.80 | DRD4 (0.47) | HRH2HRH1RETSLC6A4HTR1A | |
| SCHEMBL1728853 | 0.79 | CNR1 (0.44) | MCHR1AOC3HTR1ADRD4HTR2A | |
| SCHEMBL1727895 | 0.79 | EGLN1 (0.43) | AOC3AURKAAURKBHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |