Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728964 | 0.78 | LMNA (0.43) | THRATHRBLMNARECQLTSHR | |
| SCHEMBL9907147 | 0.78 | TSHR (0.49) | LMNATSHRALDH1A1F2RNCOA1 | |
| SCHEMBL1730641 | 0.76 | NCOA1 (0.49) | LMNATSHRALDH1A1F2RNCOA1 | |
| SCHEMBL1730615 | 0.73 | MEN1 (0.38) | LMNATSHRF2RNCOA1NCOA3 | |
| SCHEMBL1189097 | 0.67 | ALOX5 (0.55) | LMNARECQLTSHRALDH1A1F2R | |
| SCHEMBL7859993 | 0.67 | TSHR (0.46) | LMNATSHRALDH1A1HSD17B10NCOA1 | |
| SCHEMBL1860565 | 0.66 | RARA (0.48) | THRATHRBLMNARECQLHSP90AA1 | |
| SCHEMBL2772923 | 0.66 | TNFRSF1A (0.48) | LMNARECQLTSHRALDH1A1KDM4E | |
| SCHEMBL5057100 | 0.66 | TSHR (0.57) | LMNATSHRALDH1A1HSD17B10MAPK1 | |
| SCHEMBL6544965 | 0.66 | TSHR (0.39) | LMNATSHRALDH1A1HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |