Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 7/20 | 0.40 |
| ▸ | SKP1 | P63208 | 7/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 7/20 | 0.40 |
| ▸ | SORD | Q00796 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728881 | 0.90 | HCAR2 (0.36) | HCAR2ALDH1A1MAPTCKS1BSKP1 | |
| SCHEMBL1728165 | 0.89 | KDM4E (0.45) | HCAR2NPC1RAB9AHTR3AHRH4 | |
| SCHEMBL1730128 | 0.86 | HTR3A (0.43) | NPC1RAB9AHTR3AALDH1A1SMN1; SMN2 | |
| SCHEMBL1729264 | 0.86 | HTR3A (0.41) | HTR3ACKS1BSKP1SKP2 | |
| SCHEMBL1727921 | 0.85 | KDM4E (0.43) | ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL1729040 | 0.85 | HCAR2 (0.46) | HCAR2NPC1RAB9AHTR3AHRH4 | |
| SCHEMBL1727648 | 0.84 | MAPT (0.34) | RAB9AHTR3AALDH1A1MAPTHPGD | |
| SCHEMBL1727724 | 0.83 | HSD11B1 (0.40) | CKS1BSKP1SKP2 | |
| SCHEMBL1728682 | 0.83 | ACACB (0.40) | HTR3ACKS1BSKP1SKP2 | |
| SCHEMBL1727901 | 0.82 | SETDB1 (0.38) | HCAR2NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |