Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729770 | 0.89 | LMNA (0.38) | LMNAHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1727769 | 0.84 | CHRNA7 (0.43) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1730318 | 0.84 | HRH3 (0.43) | LMNAKMT2ASMN1; SMN2HTR1AHTR2A | |
| SCHEMBL1727659 | 0.81 | CRHBP (0.46) | LMNAHTTSMN1; SMN2TDP1KDM4E | |
| SCHEMBL1729359 | 0.80 | KDM1A (0.45) | LMNAKMT2ASMN1; SMN2AOC3KDM1A | |
| SCHEMBL1727687 | 0.80 | PDE10A (0.43) | LMNAKMT2ASMN1; SMN2HTR1AHTR2A | |
| SCHEMBL1728906 | 0.80 | DEGS1 (0.48) | LMNASMN1; SMN2HTR1AHTR2AKDM1A | |
| SCHEMBL1728900 | 0.77 | PRKCQ (0.38) | MEN1KMT2AHTR1AHTR2ATSHR | |
| SCHEMBL1730301 | 0.77 | LMNA (0.38) | LMNAHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1727717 | 0.77 | ALDH1A1 (0.42) | MEN1KMT2ATDP1AOC3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |