Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727689 | 0.88 | HRH3 (0.48) | HRH3MAPK14MCHR1 | |
| SCHEMBL1727579 | 0.85 | SIGMAR1 (0.52) | HRH3MAPK14CYP2D6MCHR1 | |
| SCHEMBL1728782 | 0.85 | HRH3 (0.46) | HRH3MAPK14CYP2D6MCHR1 | |
| SCHEMBL1728604 | 0.82 | DRD3 (0.59) | DRD3CYP4F2CYP4A11KDM1ADRD2 | |
| SCHEMBL1728780 | 0.82 | LTA4H (0.58) | KDM1AHRH3 | |
| SCHEMBL1727513 | 0.82 | LTA4H (0.51) | HRH3MAPK14MCHR1 | |
| SCHEMBL6081629 | 0.79 | HRH3 (0.47) | KDM1AHRH3MAPK14CYP2C9MCHR1 | |
| SCHEMBL6081541 | 0.79 | LTA4H (0.47) | HRH3MCHR1CHRM3 | |
| SCHEMBL1728829 | 0.79 | LTA4H (0.46) | HRH3MCHR1 | |
| SCHEMBL6081546 | 0.79 | HRH3 (0.42) | HRH3MAPK14MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551810-B1 | DIARYL-SUBSTITUTED CYCLIC UREA DERIVATIVES HAVING AN MCH-MODULATORY EFFECT | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-11-30 | — | — | EP | disclosed |