Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.59 |
| ▸ | KCNA5 | P22460 | 8/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728674 | 0.87 | ALDH1A1 (0.60) | DRD3KCNA5DRD2LTA4HALDH1A1 | |
| SCHEMBL6083117 | 0.84 | DRD2 (0.59) | DRD3DRD2LTA4HSIGMAR1KCNH2 | |
| SCHEMBL6081563 | 0.84 | LTA4H (0.55) | LTA4HKCNH2MCHR1 | |
| SCHEMBL1728694 | 0.83 | KDM4E (0.56) | LTA4HALDH1A1KDM4EKMT2ASIGMAR1 | |
| SCHEMBL1728503 | 0.83 | LTA4H (0.54) | LTA4HKDM4ESIGMAR1KCNH2MCHR1 | |
| SCHEMBL1729209 | 0.82 | DRD3 (0.56) | DRD3DRD2CYP4F2CYP4A11KDM1A | |
| SCHEMBL1728438 | 0.82 | LTA4H (0.56) | LTA4HKCNH2MCHR1 | |
| SCHEMBL6081977 | 0.80 | LTA4H (0.56) | DRD3DRD2LTA4HALDH1A1MEN1 | |
| SCHEMBL1728741 | 0.80 | LTA4H (0.51) | DRD2LTA4HKCNH2MCHR1 | |
| SCHEMBL6081709 | 0.80 | TMEM97 (0.69) | LTA4HALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551810-B1 | DIARYL-SUBSTITUTED CYCLIC UREA DERIVATIVES HAVING AN MCH-MODULATORY EFFECT | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-11-30 | — | — | EP | disclosed |