Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 13/20 | 0.38 |
| ▸ | SKP1 | P63208 | 13/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 13/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730142 | 0.90 | ABL1 (0.37) | — | |
| SCHEMBL1729779 | 0.89 | SMO (0.34) | CKS1BSKP1SKP2KCNH2DGAT1 | |
| SCHEMBL1730195 | 0.86 | HCAR2 (0.46) | HTR3ACKS1BSKP1SKP2 | |
| SCHEMBL1730251 | 0.86 | DPP4 (0.42) | HTR3ACKS1BSKP1SKP2CXCR3 | |
| SCHEMBL1727921 | 0.85 | KDM4E (0.43) | — | |
| SCHEMBL1727744 | 0.84 | RXRA (0.43) | CKS1BSKP1SKP2 | |
| SCHEMBL1728165 | 0.84 | KDM4E (0.45) | HTR3A | |
| SCHEMBL1730128 | 0.84 | HTR3A (0.43) | HTR3A | |
| SCHEMBL1727724 | 0.83 | HSD11B1 (0.40) | CKS1BSKP1SKP2 | |
| SCHEMBL1728682 | 0.82 | ACACB (0.40) | HTR3ACKS1BSKP1SKP2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |