Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 5/20 | 0.36 |
| ▸ | F13A1 | P00488 | 2/20 | 0.36 |
| ▸ | TGM1 | P22735 | 2/20 | 0.36 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727724 | 0.91 | HSD11B1 (0.40) | ACACBCKS1BSKP1SKP2 | |
| SCHEMBL1727875 | 0.89 | ACACB (0.40) | ACACBCKS1BSKP1SKP2 | |
| SCHEMBL1728808 | 0.88 | PKM (0.37) | ACACBCKS1BSKP1SKP2PDE10A | |
| SCHEMBL1727768 | 0.87 | HRH3 (0.37) | ACACBHTR1ACKS1BSKP1SKP2 | |
| SCHEMBL1727921 | 0.85 | KDM4E (0.43) | HTR1AHTR2ATSHR | |
| SCHEMBL1728165 | 0.85 | KDM4E (0.45) | DRD3HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1727648 | 0.83 | MAPT (0.34) | HTR3APDE10A | |
| SCHEMBL1729592 | 0.83 | PTGES (0.42) | PDE10A | |
| SCHEMBL1730195 | 0.83 | HCAR2 (0.46) | HTR3ACKS1BSKP1SKP2 | |
| SCHEMBL1728881 | 0.82 | HCAR2 (0.36) | CKS1BSKP1SKP2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |