Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13834151 | 0.85 | NPC1 (0.42) | CREBBPMTNR1APOLBHTTLMNA | |
| SCHEMBL22415249 | 0.84 | MTNR1A (0.36) | BAZ2BCREBBPMTNR1APOLBHTT | |
| SCHEMBL8959923 | 0.84 | KDM4E (0.37) | HTR6CREBBPMTNR1AGAAHPGD | |
| SCHEMBL29507033 | 0.84 | LMNA (0.40) | BAZ2BCREBBPMTNR1AHTTGAA | |
| SCHEMBL2470098 | 0.84 | LMNA (0.40) | BAZ2BCREBBPMTNR1AHTTGAA | |
| SCHEMBL2476989 | 0.84 | ABCB11 (0.46) | BAZ2BMTNR1APOLBMEN1KMT2A | |
| SCHEMBL27923794 | 0.83 | SPR (0.46) | CYP3A4MTNR1APOLBHTTGAA | |
| SCHEMBL13172044 | 0.82 | MTNR1A (0.55) | BAZ2BCREBBPMTNR1APOLBHTT | |
| SCHEMBL1051164 | 0.80 | CREBBP (0.50) | CREBBPPOLBMEN1KMT2AHTT | |
| SCHEMBL29386752 | 0.80 | CREBBP (0.50) | CREBBPPOLBMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531488-B1 | INDIRUBIN-3'-OXIME DERIVATIVES AS POTENT CYCLIN DEPENDENT KINASE INHIBITORS | ANYGEN CO LTD (KR) | 2015-12-09 | — | — | EP | disclosed |