Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119735 | 0.90 | HSD11B1 (0.32) | OPRM1OPRD1OPRK1 | |
| SCHEMBL17320563 | 0.83 | NPSR1 (0.31) | — | |
| SCHEMBL12872912 | 0.79 | ALOX15 (0.41) | — | |
| SCHEMBL14476933 | 0.77 | ALDH1A1 (0.34) | — | |
| SCHEMBL2740760 | 0.77 | — | — | |
| SCHEMBL22314809 | 0.77 | EPHX2 (0.35) | — | |
| SCHEMBL17322538 | 0.76 | ALOX5AP (0.33) | — | |
| SCHEMBL14982576 | 0.75 | HSD11B1 (0.31) | — | |
| SCHEMBL13779647 | 0.75 | HSD11B1 (0.31) | — | |
| SCHEMBL13564204 | 0.75 | HSD11B1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290435-B2 | Molecular glass of spirofluorene derivative, preparation method thereof and use thereof in photo-etching | Technical Institute of Physics and Chemistry of the Chinese Academy of Sciences (CN) | 2016-03-22 | — | — | US | disclosed |
| US-20150353468-A1 | MOLECULAR GLASS OF SPIROFLUORENE DERIVATIVE, PREPARATION METHOD THEREOF AND USE THEREOF IN PHOTO-ETCHING | Technical Institute of Physics and Chemistry of the Chinese Academy of Sciences (CN) | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353468-A1 | MOLECULAR GLASS OF SPIROFLUORENE DERIVATIVE, PREPARATION METHOD THEREOF AND USE THEREOF IN PHOTO-ETCHING | PDGFRA, ARHGEF12, GLI2 | OPRM1 3934/4885OPRD1 2641/4885OPRK1 3217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.