Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 5/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747748 | 0.89 | KDM4E (0.59) | KDM4EPPARGPPARDPPARALTA4H | |
| SCHEMBL853597 | 0.87 | LTA4H (0.64) | KDM4EPPARGPPARDPPARALTA4H | |
| SCHEMBL30176255 | 0.87 | LTA4H (0.64) | KDM4EPPARGPPARDPPARALTA4H | |
| SCHEMBL17320598 | 0.87 | KDM4E (0.63) | KDM4EPPARGPPARDPPARALTA4H | |
| SCHEMBL23701834 | 0.86 | PPARG (0.68) | KDM4EPPARGPPARDPPARALTA4H | |
| SCHEMBL23701738 | 0.84 | PPARG (0.59) | KDM4EPPARGPPARDPPARALTA4H | |
| SCHEMBL15747662 | 0.83 | KDM4E (0.60) | KDM4ETRPM8MEN1KMT2APOLB | |
| SCHEMBL2686551 | 0.81 | KDM4E (0.77) | KDM4ETRPM8MEN1KMT2APOLB | |
| SCHEMBL15747724 | 0.81 | HTR1B (0.59) | KDM4EPPARGPPARDPPARAMEN1 | |
| SCHEMBL15747725 | 0.81 | HTR1B (0.62) | KDM4ELTA4HPLA2G2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004718-B2 | Erythropoietin expression promoter | TOHOKU UNIVERSITY (JP) | 2018-06-26 | — | — | US | disclosed |
| US-20150353489-A1 | Erythropoietin Expression Promoter | KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION KANAGAWA CHILDREN'S MEDICAL CENTER (JP) | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353489-A1 | Erythropoietin Expression Promoter | EPOR, NFE2L2, FOXO1 | KDM4E 3503/4885PPARG 393/4885PPARD 536/4885 |
| US-10004718-B2 | Erythropoietin expression promoter | EPOR, NFE2L2, FOXO1 | KDM4E 3503/4885PPARG 393/4885PPARD 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.