SCHEMBL23701738

SCHEMBL23701738

COC(=O)Cc1c[nH]c2ccc(OCc3cccc(C)c3)cc12

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.59
PPARD Q03181 1/20 0.59
PPARA Q07869 1/20 0.59
LTA4H P09960 7/20 0.56
PLA2G2A P14555 7/20 0.56
HTR1D P28221 3/20 0.55
HTR1A P08908 1/20 0.55
HTR1B P28222 1/20 0.55
TRPM8 Q7Z2W7 3/20 0.54
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
HSP90AA1 P07900 1/20 0.52
HSP90AB1 P08238 1/20 0.52
KDM4E B2RXH2 2/20 0.50
POLB P06746 1/20 0.49
MAPT P10636 1/20 0.49
ICMT O60725 1/20 0.48
MAOB P27338 1/20 0.48
SLC6A4 P31645 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23701860 0.89 PPARG (0.73) PPARGPPARDPPARALTA4HPLA2G2A
SCHEMBL853597 0.89 LTA4H (0.64) PPARGPPARDPPARALTA4HPLA2G2A
SCHEMBL30176255 0.89 LTA4H (0.64) PPARGPPARDPPARALTA4HPLA2G2A
SCHEMBL23701834 0.88 PPARG (0.68) PPARGPPARDPPARALTA4HPLA2G2A
SCHEMBL17320596 0.84 KDM4E (0.53) PPARGPPARDPPARALTA4HPLA2G2A
SCHEMBL15747748 0.84 KDM4E (0.59) PPARGPPARDPPARALTA4HPLA2G2A
SCHEMBL6219226 0.81 TRPM8 (0.70) PPARGPPARDPPARALTA4HPLA2G2A
SCHEMBL15747662 0.81 KDM4E (0.60) HTR1DHTR1AHTR1BTRPM8MEN1
SCHEMBL6664147 0.80 ALDH1A1 (0.60) PPARGPPARDPPARALTA4HPLA2G2A
SCHEMBL21255987 0.80 MTNR1A (0.59) HTR1DKDM4EPOLBMAPTICMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12150447-B2 Plant growth regulator UNIVERSITY OF WASHINGTON (US) 2024-11-26 US disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210235697-A1 PLANT GROWTH REGULATOR ING2, GHRHR, MYB PPARG 657/4885PPARD 2304/4885PPARA 2805/4885
US-12150447-B2 Plant growth regulator ING2, GHRHR, MYB PPARG 657/4885PPARD 2304/4885PPARA 2805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.