Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.49 |
| ▸ | ABAT | P80404 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14035450 | 0.90 | XDH (0.58) | XDHCYP1A2ALDH5A1ABATVCAM1 | |
| SCHEMBL3601360 | 0.83 | XDH (0.51) | XDHCYP1A2ALDH5A1ABATVCAM1 | |
| SCHEMBL531803 | 0.81 | XDH (0.69) | XDHALDH5A1ABATVCAM1ALDH1A1 | |
| SCHEMBL12777072 | 0.79 | ALDH1A1 (0.54) | XDHCYP1A2ALDH5A1ABATVCAM1 | |
| SCHEMBL1814040 | 0.78 | ALDH1A1 (0.50) | XDHALDH5A1ABATVCAM1TSHR | |
| SCHEMBL19785604 | 0.78 | TSHR (0.53) | XDHALDH5A1ABATVCAM1TSHR | |
| SCHEMBL1826371 | 0.77 | ALDH5A1 (0.58) | XDHCYP1A2ALDH5A1ABATVCAM1 | |
| SCHEMBL29952850 | 0.77 | ALDH5A1 (0.58) | XDHCYP1A2ALDH5A1ABATVCAM1 | |
| SCHEMBL335971 | 0.77 | ALDH5A1 (0.62) | XDHCYP1A2ALDH5A1ABATVCAM1 | |
| SCHEMBL814444 | 0.76 | SRC (0.48) | CYP1A2TSHRALDH1A1ALDH1A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111763191-A | Preparation method of DMXAA | 河北中科金辉药业有限公司 | 2020-10-13 | — | — | CN | disclosed |
| US-9580379-B2 | Xanthine oxidase inhibitors and methods of use | BAYLOR COLLEGE OF MEDICINE (US) | 2017-02-28 | — | — | US | disclosed |
| US-20150353471-A1 | XANTHINE OXIDASE INHIBITORS AND METHODS OF USE | BAYLOR COLLEGE OF MEDICINE | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353471-A1 | XANTHINE OXIDASE INHIBITORS AND METHODS OF USE | XDH, PNPO, AOX1 | XDH 1/4885CYP1A2 104/4885ALDH5A1 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.