Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3601360 | 0.88 | XDH (0.51) | ALDH1A1TDP1XDHALDH5A1ABAT | |
| SCHEMBL17320649 | 0.78 | XDH (0.53) | ALDH1A1TDP1XDHALDH5A1ABAT | |
| SCHEMBL1820951 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL28303467 | 0.76 | XDH (0.60) | ALDH1A1XDHALDH5A1ABATVCAM1 | |
| SCHEMBL1812370 | 0.75 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRGRIN2DGRIN3B | |
| SCHEMBL531803 | 0.75 | XDH (0.69) | ALDH1A1XDHALDH5A1ABATVCAM1 | |
| SCHEMBL8440730 | 0.75 | TSHR (0.58) | ALDH1A1TDP1TSHRPOLBKMT2A | |
| SCHEMBL19970551 | 0.74 | XDH (0.48) | ALDH1A1TDP1XDHALDH5A1ABAT | |
| SCHEMBL6715667 | 0.74 | ALDH1A1 (0.61) | ALDH1A1XDHALDH5A1ABATVCAM1 | |
| SCHEMBL14035450 | 0.74 | XDH (0.58) | ALDH1A1TDP1XDHALDH5A1ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119100946-A | Synthesis method of key intermediate of rilpivirine | 石家庄龙泽制药股份有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-102177135-A | Acylaminobenzamide derivatives | BAYER CROPSCIENCE AG | 2011-09-07 | — | — | CN | disclosed |
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-08-18 | — | — | US | disclosed |
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-08-18 | — | — | US | disclosed |
| EP-2318358-A2 | ACYLAMINOBENZAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010015355-A2 | NOVEL ACYLAMINOBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015355-A2 | NOVEL ACYLAMINOBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-02-11 | — | — | WO | disclosed |
| US-7585861-B2 | HIV replication inhibitors; for (multi)drug resistant HIV infection | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-09-08 | — | — | US | disclosed |
| US-7585861-B2 | HIV replication inhibitors; for (multi)drug resistant HIV infection | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-09-08 | — | — | US | disclosed |
| US-20070037811-A1 | HIV replication inhibitors; for (multi)drug resistant HIV infection | BMO BANK N.A., AS ADMINISTRATIVE AGENT | 2007-02-15 | — | — | US | disclosed |
| US-20070037811-A1 | HIV replication inhibitors; for (multi)drug resistant HIV infection | BMO BANK N.A., AS ADMINISTRATIVE AGENT | 2007-02-15 | — | — | US | disclosed |
| US-20070027143-A1 | Novel substituted 2,3-benzodiazepine derivatives | IVAX DRUG RESEARCH INSTITUTE, LTD. (HU) | 2007-02-01 | — | — | US | disclosed |
| EP-1592673-A4 | NOVEL SUBSTITUTED 2,3-BENZODIAZEPINE DERIVATIVES | IVAX DRUG RES INST LTD (HU) | 2006-10-25 | — | — | EP | disclosed |
| CN-1747938-A | Novel substituted 2, 3-benzodiazepine * derivatives | IVAX INST FOR DRUG RES LTD (HU) | 2006-03-15 | — | — | CN | disclosed |
| EP-1592673-A2 | NOVEL SUBSTITUTED 2,3-BENZODIAZEPINE DERIVATIVES | Ivax Institute for Drug Research, Ltd. (HU) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004069197-A2 | NOVEL SUBSTITUTED 2,3-BENZODIAZEPINE DERIVATIVES | IVAX CORPORATION (US) | 2004-08-19 | — | — | WO | disclosed |
| EP-0041675-B1 | 4-HALOGEN-5-(TRICHLOROMETHYL-PHENYL)-OXAZOLE DERIVATIVES, PROCESS FOR PREPARING THEM AND RADIATION-SENSITIVE COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-11 | — | — | EP | disclosed |
| US-4371607-A | 4-Halogeno-5-(halogenomethyl-phenyl)-oxazole derivatives, a process for the preparation thereof, and radiation-sensitive compositions containing these derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-01 | — | — | US | disclosed |
| EP-0041675-A2 | 4-Halogen-5-(trichloromethyl-phenyl)-oxazole derivatives, process for preparing them and radiation-sensitive compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-16 | — | — | EP | disclosed |
| US-4017313-A | Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | KCNB1, KCNA5, KCNA7 | ALDH1A1 271/4885TDP1 3523/4885XDH 3525/4885 |
| US-20070037811-A1 | HIV replication inhibitors; for (multi)drug resistant HIV infection | REV1, CCNI, MCM6 | ALDH1A1 3720/4885TDP1 2151/4885XDH 915/4885 |
| US-20070027143-A1 | Novel substituted 2,3-benzodiazepine derivatives | GABRB2, GABRB3, GABRA2 | ALDH1A1 844/4885TDP1 3724/4885XDH 944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.