Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25608187 | 0.85 | NPC1 (0.40) | LMNAMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL17658595 | 0.85 | ALOX5 (0.37) | — | |
| SCHEMBL18212070 | 0.84 | NPC1 (0.41) | LMNAMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL18212124 | 0.83 | PLA2G2A (0.42) | LMNAMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL17083563 | 0.82 | MAPT (0.40) | LMNAMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL29294357 | 0.82 | MGLL (0.36) | LMNAMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL31195961 | 0.82 | AHR (0.43) | LMNAMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL27111889 | 0.82 | AHR (0.43) | LMNAMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL17285617 | 0.81 | HPGD (0.39) | LMNAMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL22259437 | 0.81 | NPC1 (0.41) | LMNAMAPTNPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150357575-A1 | AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-12-10 | — | — | US | disclosed |