Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17345924 | 0.84 | NPC1 (0.54) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL1906153 | 0.82 | SIRT2 (0.63) | SIRT2KIF11 | |
| SCHEMBL30556728 | 0.80 | GAA (0.65) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL17335830 | 0.78 | GAA (0.50) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL17345938 | 0.77 | NPC1 (0.51) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL17346082 | 0.75 | MAPT (0.55) | TSHRGAAKIF11ALDH1A1MEN1 | |
| SCHEMBL17345922 | 0.75 | SMN1; SMN2 (0.54) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL16653155 | 0.73 | KIF11 (0.53) | KIF11ALDH1A1MEN1KMT2A | |
| SCHEMBL1706149 | 0.72 | SIRT2 (0.47) | SIRT2KIF11ALDH1A1HTT | |
| SCHEMBL7206096 | 0.72 | KIF11 (0.57) | SIRT2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11370736-B2 | Synthesis of fluoro hemiacetals via transition metal-catalyzed fluoro ester and carboxamide hydrogenation | TRIAD NATIONAL SECURITY, LLC (US) | 2022-06-28 | — | — | US | disclosed |
| US-11370736-B2 | Synthesis of fluoro hemiacetals via transition metal-catalyzed fluoro ester and carboxamide hydrogenation | TRIAD NATIONAL SECURITY, LLC (US) | 2022-06-28 | — | — | US | disclosed |
| US-20200308089-A1 | SYNTHESIS OF FLUORO HEMIACETALS VIA TRANSITION METAL-CATALYZED FLUORO ESTER AND CARBOXAMIDE HYDROGENATION | U.S. DEPARTMENT OF ENERGY | 2020-10-01 | — | — | US | disclosed |
| US-20200308089-A1 | SYNTHESIS OF FLUORO HEMIACETALS VIA TRANSITION METAL-CATALYZED FLUORO ESTER AND CARBOXAMIDE HYDROGENATION | U.S. DEPARTMENT OF ENERGY | 2020-10-01 | — | — | US | disclosed |
| US-10550139-B2 | Polydentate ligands and their complexes for molecular catalysis | TRIAD NATIONAL SECURITY, LLC (US) | 2020-02-04 | — | — | US | disclosed |
| US-20170088571-A1 | POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS | TRIAD NATIONAL SECURITY, LLC | 2017-03-30 | — | — | US | disclosed |
| US-20170088571-A1 | POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS | TRIAD NATIONAL SECURITY, LLC | 2017-03-30 | — | — | US | disclosed |
| WO-2015191505-A1 | POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2015-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088571-A1 | POLYDENTATE LIGANDS AND THEIR COMPLEXES FOR MOLECULAR CATALYSIS | NANS, NCL, NCLN | SIRT2 2679/4885TSHR 4074/4885GAA 4253/4885 |
| US-10550139-B2 | Polydentate ligands and their complexes for molecular catalysis | NANS, NCL, NCLN | SIRT2 2679/4885TSHR 4074/4885GAA 4253/4885 |
| US-20200308089-A1 | SYNTHESIS OF FLUORO HEMIACETALS VIA TRANSITION METAL-CATALYZED FLUORO ESTER AND CARBOXAMIDE HYDROGENATION | FH, HIRA, HNF4A | SIRT2 223/4885TSHR 1790/4885GAA 1659/4885 |
| US-11370736-B2 | Synthesis of fluoro hemiacetals via transition metal-catalyzed fluoro ester and carboxamide hydrogenation | FH, HIRA, HNF4A | SIRT2 223/4885TSHR 1790/4885GAA 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.