SCHEMBL1734665

SCHEMBL1734665

COc1c(C(=O)c2ccccc2)cc(O)c(O)c1OC.[NaH]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.59
LMNA P02545 5/20 0.59
HPGD P15428 2/20 0.59
KDM4E B2RXH2 2/20 0.59
HSD17B10 Q99714 2/20 0.59
CYP3A4 P08684 1/20 0.59
RECQL P46063 1/20 0.59
MAPK1 P28482 3/20 0.55
HTT P42858 3/20 0.55
ALDH1A1 P00352 3/20 0.55
CYP1A2 P05177 1/20 0.55
PGR P06401 1/20 0.55
CYP2D6 P10635 1/20 0.55
SLC6A2 P23975 1/20 0.55
PDE4A P27815 1/20 0.55
CYP2C19 P33261 1/20 0.55
HRH1 P35367 1/20 0.55
SLC6A3 Q01959 1/20 0.55
PDE4D Q08499 1/20 0.55
ALOX15 P16050 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22588882 1.00 MAPT (0.59) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL480277 0.98 MAPT (0.60) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL30062998 0.97 MAPT (0.59) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL29709425 0.97 MAPT (0.59) MAPTLMNAHPGDKDM4EHSD17B10
Sulfuric Acid SCHEMBL2878069 0.90 MAPT (0.52) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL27864162 0.86 LMNA (0.60) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL27976994 0.86 MAPT (0.60) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL6112746 0.83 MAPT (0.58) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL2474578 0.83 MAPT (0.60) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL687665 0.81 MAPT (0.59) MAPTLMNAHPGDKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2172185-B1 Cosmetic material comprising octyl hydroxy stearate oligomer PARAHERMOSA CO LTD (JP) 2011-11-23 EP claimed
US-12600821-B2 Crosslinked organosilicon resin, a method for producing same, and a cosmetic SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-04-14 US disclosed
US-12595182-B2 Method for producing chemical-treated metal oxide powder TOKUYAMA CORPORATION (JP) 2026-04-07 US disclosed
US-12582590-B2 Transparent liquid composition and cosmetic containing said composition SEIWA KASEI COMPANY, LIMITED (JP) 2026-03-24 US disclosed
EP-3822303-B1 CROSSLINKED ORGANOSILICON RESIN, METHOD FOR PRODUCING SAME, AND COSMETIC SHINETSU CHEMICAL CO (JP) 2026-03-04 EP disclosed
US-20250324973-A1 Pest Control Composition and Control Method SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-10-23 US disclosed
EP-3719056-B1 ORGANIC GROUP-MODIFIED ORGANOSILICON RESIN, PRODUCTION METHOD THEREOF, AND COSMETIC SHINETSU CHEMICAL CO (JP) 2025-08-27 EP disclosed
CN-114340585-B Solid cosmetic material 信越化学工业株式会社 2025-05-20 CN disclosed
CN-113645952-B Oily mixture composition, cosmetic, and method for producing cosmetic 信越化学工业株式会社 2025-05-02 CN disclosed
US-20250064061-A1 METHOD FOR CONTROLLING NOXIOUS ARTHROPODS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-02-27 US disclosed
EP-1481660-B1 Cosmetic SHINETSU CHEMICAL CO (JP) 2008-02-20 EP disclosed
US-20080031906-A1 Cosmetic Composition and Method for Producing the Same HAKUTO CO., LTD. (JP) 2008-02-07 US disclosed
US-20070254947-A1 Composition for external use ROHTO PHARMACEUTICAL CO., LTD. (JP) 2007-11-01 US disclosed
EP-1820538-A1 COSMETICS AND PROCESS FOR PRODUCTION THEREOF Hakuto Co., Ltd (JP) 2007-08-22 EP disclosed
CN-1938000-A Cosmetic containing siloxane polymer SHINETSU CHEMICAL CO (JP) 2007-03-28 CN disclosed
WO-2006137576-A1 COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2006-12-28 WO disclosed
EP-1736138-A1 COSMETIC PREPARATION CONTAINING SILICONE POLYMER Shin-Etsu Chemical Company, Ltd. (JP) 2006-12-27 EP disclosed
US-20040241126-A1 Cosmetic SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-12-02 US disclosed
EP-1481660-A1 Cosmetic Shin-Etsu Chemical Co., Ltd. (JP) 2004-12-01 EP disclosed
CN-1545403-A Modified inorganic fine particles for cosmetic and cosmetic ��ý���ɹ�ҵ��ʽ���� 2004-11-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040241126-A1 Cosmetic SGMS1, ALG3, RIF1 MAPT 4522/4885LMNA 2493/4885HPGD 3493/4885
US-20080031906-A1 Cosmetic Composition and Method for Producing the Same LIPA, CUTA, PLIN3 MAPT 3101/4885LMNA 201/4885HPGD 2438/4885
US-12600821-B2 Crosslinked organosilicon resin, a method for producing same, and a cosmetic DEGS1, HACL2, GAR1 MAPT 4729/4885LMNA 1942/4885HPGD 3319/4885
US-12595182-B2 Method for producing chemical-treated metal oxide powder RPP30, MYH10, SOD1 MAPT 262/4885LMNA 1063/4885HPGD 4442/4885
US-12582590-B2 Transparent liquid composition and cosmetic containing said composition GK, CUTA, GHDC MAPT 2880/4885LMNA 266/4885HPGD 1961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.