SCHEMBL17355698

SCHEMBL17355698

CS(=O)(=O)Oc1c(F)cccc1C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 3/20 0.40
KIF11 P52732 2/20 0.37
EPAS1 Q99814 1/20 0.35
CYP2D6 P10635 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
NFE2L2 Q16236 2/20 0.35
KAT6A Q92794 1/20 0.35
AR P10275 1/20 0.35
HSD11B1 P28845 2/20 0.34
NR1H2 P55055 2/20 0.34
NR1H3 Q13133 2/20 0.34
KMT2A Q03164 2/20 0.33
GAA P10253 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15453749 0.89 KMT2A (0.37) SLC22A12KIF11CYP2D6NFE2L2HSD11B1
SCHEMBL3755699 0.83 PKM (0.36) EPAS1KMT2AGAA
SCHEMBL17355704 0.81 RORC (0.40) SLC22A12HSD11B1NR1H2NR1H3KMT2A
SCHEMBL17352142 0.76 KIF11 (0.37) SLC22A12KIF11NFE2L2KAT6ANR1H2
SCHEMBL22208564 0.76 AR (0.44) SLC22A12CYP2D6SLC6A2SLC6A4NFE2L2
SCHEMBL31697313 0.76 AR (0.44) SLC22A12CYP2D6SLC6A2SLC6A4NFE2L2
SCHEMBL15453710 0.75 KIF11 (0.36) KIF11
SCHEMBL6941315 0.73 SLC22A12 (0.40) SLC22A12NFE2L2HSD11B1KMT2AGAA
SCHEMBL17355737 0.72 KDM4E (0.40) KIF11KMT2A
SCHEMBL15453472 0.72 HSD11B1 (0.36) SLC22A12NFE2L2HSD11B1NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 SLC22A12 236/4885KIF11 2611/4885EPAS1 1684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.