SCHEMBL17355704

SCHEMBL17355704

CS(=O)(=O)Oc1c(Cl)cccc1C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RORC P51449 7/20 0.40
HSD11B1 P28845 1/20 0.38
SLC22A12 Q96S37 1/20 0.37
P2RX7 Q99572 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35
TYK2 P29597 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
MCL1 Q07820 1/20 0.33
NOTUM Q6P988 1/20 0.33
PTGS2 P35354 1/20 0.33
RARG P13631 1/20 0.33
PPARG P37231 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15453749 0.88 KMT2A (0.37) HSD11B1SLC22A12MEN1KMT2ANR1H2
SCHEMBL17355698 0.81 SLC22A12 (0.40) HSD11B1SLC22A12MEN1KMT2ANR1H2
SCHEMBL15453710 0.74 KIF11 (0.36) CA1CA2CA9PTGS2
SCHEMBL29183881 0.74 MCL1 (0.42) RORCHSD11B1SLC22A12P2RX7MEN1
SCHEMBL17355738 0.73 TYK2 (0.40) RORCKMT2ATYK2L3MBTL1NOTUM
SCHEMBL15567907 0.73 LMNA (0.37) RORCSLC22A12P2RX7KMT2ANR1H2
SCHEMBL10977634 0.73 P2RX7 (0.37) RORCHSD11B1SLC22A12P2RX7TYK2
SCHEMBL8907308 0.72 HSD11B1 (0.36) HSD11B1MEN1KMT2A
SCHEMBL6941315 0.72 SLC22A12 (0.40) HSD11B1SLC22A12MEN1KMT2APPARG
SCHEMBL15453472 0.71 HSD11B1 (0.36) HSD11B1SLC22A12MEN1KMT2ANR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 RORC 2967/4885HSD11B1 2662/4885SLC22A12 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.