SCHEMBL3243631

SCHEMBL3243631

C=CC(=O)OCCNC(=O)Nc1ccccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MARS1 P56192 1/20 0.44
THRB P10828 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 6/20 0.42
MAPT P10636 4/20 0.42
MAPK1 P28482 1/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 2/20 0.39
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ITGB3 P05106 1/20 0.39
ITGAV P06756 1/20 0.39
POLB P06746 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3252282 0.91 MARS1 (0.47) MARS1THRBALDH1A1GAAMAPT
SCHEMBL3252175 0.87 TRPV1 (0.44) THRBALDH1A1GAAMAPTKMT2A
SCHEMBL4930932 0.87 EPHX1 (0.41) THRBALDH1A1MAPTKMT2AKDM4E
SCHEMBL1735947 0.86 GAA (0.43) MARS1THRBALDH1A1GAAMAPT
SCHEMBL3250210 0.85 ITGB3 (0.57) ALDH1A1GAAMAPTNPC1RAB9A
SCHEMBL3248419 0.84 HDAC1 (0.49) KDM4E
SCHEMBL3251793 0.83 EPHX1 (0.60) ALDH1A1GAAMAPTKMT2AKDM4E
SCHEMBL3252284 0.83 GOT1 (0.48) THRBALDH1A1MAPTKMT2AMEN1
SCHEMBL5705948 0.82 THRB (0.41) THRBALDH1A1GAAMAPTMAPK1
SCHEMBL3254771 0.82 KCNMA1 (0.46) GAAMAPTMAPK1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521927-B1 POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING THE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2021-10-27 EP disclosed
US-10649337-B2 Positive type lithographic printing plate precursor, method of producing same, and method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2020-05-12 US disclosed
EP-3521927-A1 POSITIVE PLANOGRAPHIC PRINTING ORIGINAL PLATE AND METHOD FOR MANUFACTURING SAME, AND METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2019-08-07 EP disclosed
US-20190212652-A1 POSITIVE TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PRODUCING SAME, AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2019-07-11 US disclosed
EP-2538275-B1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2014-10-29 EP disclosed
EP-1705004-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-09-25 EP disclosed
US-20130004897-A1 METHOD FOR MANUFACTURING A PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2013-01-03 US disclosed
EP-2538275-A1 PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2012-12-26 EP disclosed
EP-1136886-B1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORP (JP) 2010-05-19 EP disclosed
US-20090246693-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
EP-1705004-A1 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-09-27 EP disclosed
US-6517987-B2 Mixture of 1,2-naphthoquinone-2-diazide-5-sulfonic acid and polymer FUJI PHOTO FILM CO., LTD. (JP) 2003-02-11 US disclosed
US-20010041299-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORPORATION (JP) 2001-11-15 US disclosed
EP-1136886-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate Fuji Photo Film Co., Ltd. (JP) 2001-09-26 EP disclosed