SCHEMBL17372402

SCHEMBL17372402

CCCC(NO)C(=O)NC(=O)Nc1nc(SC)nc2[nH]cnc12

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ ADORA3 P0DMS8 1/20 0.30
▸ ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17372613 0.82 SMN1; SMN2 (0.35) —
SCHEMBL546675 0.80 — —
SCHEMBL17372419 0.79 CYP1A2 (0.30) CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL17372415 0.79 CYP1A2 (0.30) CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL28960555 0.78 MEN1 (0.38) CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL29278769 0.71 SPHK1 (0.32) CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL6765504 0.71 KDM4E (0.48) CYP1A2CYP2D6CYP2C19ADORA3ADORA2A
SCHEMBL25244196 0.70 CYP1A2 (0.31) CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL28960558 0.69 CYP1A2 (0.41) CYP1A2CYP3A4CYP2D6CYP2C19ADORA3
SCHEMBL29124870 0.68 SYK (0.37) CYP1A2CYP3A4CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238212-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2024-07-18 — — US disclosed
US-20240218399-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS SUZHOU ABOGEN BIOSCIENCES CO LTD (CN) 2024-07-04 — — US disclosed
WO-2024140624-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2024-07-04 — — WO disclosed
WO-2024134511-A2 LIPID NANOPARTICLE COMPOSITION Seqirus Inc. (US) 2024-06-27 — — WO disclosed
WO-2024134512-A1 LIPID NANOPARTICLE COMPOSITION Seqirus Inc. (US) 2024-06-27 — — WO disclosed
US-20240189408-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. 2024-06-13 — — US disclosed
EP-3917503-B1 METHODS OF PREPARING LIPID NANOPARTICLES MODERNATX INC (US) 2024-05-08 — — EP disclosed
US-11969506-B2 Lipid nanoparticle formulation MODERNATX, INC. (US) 2024-04-30 — — US disclosed
WO-2024084397-A1 VACCINATION AGAINST PNEUMOCCOCAL AND COVID-19 INFECTIONS PFIZER INC. (US) 2024-04-25 — — WO disclosed
US-20240131150-A1 NUCLEIC ACID VACCINES FOR CORONAVIRUS SUZHOU ABOGEN BIOSCIENCES CO LTD (CN) 2024-04-25 — — US disclosed
WO-2017066793-A1 MRNA CAP ANALOGS AND METHODS OF MRNA CAPPING MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017066781-A1 MRNA CAP ANALOGS WITH MODIFIED PHOSPHATE LINKAGE MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017066797-A1 TRINUCLEOTIDE MRNA CAP ANALOGS MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017066782-A1 HYDROPHOBIC MRNA CAP ANALOGS MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017066789-A1 MRNA CAP ANALOGS WITH MODIFIED SUGAR MODERNATX, INC. (US) 2017-04-20 — — WO disclosed
WO-2017049245-A2 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2017-03-23 — — WO disclosed
WO-2017049286-A1 POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER MODERNA THERAPEUTICS, INC. (US) 2017-03-23 — — WO disclosed
WO-2017049275-A2 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION MODERNA THERAPEUTICS, INC. (US) 2017-03-23 — — WO disclosed
WO-2015196118-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2015-12-23 — — WO disclosed
WO-2015196130-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2015-12-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11969506-B2 Lipid nanoparticle formulation TTPA, SREBF1, SREBF2 CYP1A2 2248/4885CYP3A4 2259/4885CYP2D6 1756/4885
US-20240238212-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS CETP, NPC1, LCAT CYP1A2 4101/4885CYP3A4 4049/4885CYP2D6 3915/4885
US-20240189408-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS MT-CO2, CYB5R3, COX5A CYP1A2 400/4885CYP3A4 425/4885CYP2D6 901/4885
US-20240131150-A1 NUCLEIC ACID VACCINES FOR CORONAVIRUS SARS1, POLRMT, SARNP CYP1A2 4592/4885CYP3A4 4664/4885CYP2D6 4255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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