Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17385329 | 0.88 | PIN1 (0.46) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL17385023 | 0.86 | MAPT (0.48) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL17385292 | 0.85 | NPC1 (0.51) | NPC1MEN1KMT2ARAB9ADHODH | |
| SCHEMBL17385434 | 0.85 | DNM1L (0.48) | NPC1RAB9ADHODHSMN1; SMN2PIN1 | |
| SCHEMBL17385433 | 0.84 | TP53 (0.54) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL17385042 | 0.83 | MAPT (0.45) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL17385379 | 0.83 | TP53 (0.52) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL17385049 | 0.82 | DGAT1 (0.51) | NPC1MEN1KMT2ARAB9APIN1 | |
| SCHEMBL22677838 | 0.82 | PIN1 (0.47) | NPC1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL17385436 | 0.82 | TP53 (0.52) | NPC1KMT2ARAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153756-A1 | ANTI-INFECTIVE COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2022-05-19 | — | — | US | disclosed |
| EP-3157904-B1 | ANTI-INFECTIVE COMPOUNDS | PASTEUR INSTITUT KOREA (KR) | 2020-11-18 | — | — | EP | disclosed |
| US-20170121349-A1 | Anti-Infective Compounds | INSTITUT PASTEUR KOREA (KR) | 2017-05-04 | — | — | US | disclosed |
| WO-2015193506-A1 | ANTI-INFECTIVE COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2015-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153756-A1 | ANTI-INFECTIVE COMPOUNDS | RABGGTB, ELANE, SERPINB1 | NPC1 402/4885MEN1 3685/4885KMT2A 4781/4885 |
| US-20170121349-A1 | Anti-Infective Compounds | FNTB, LSS, PGLS | NPC1 452/4885MEN1 3545/4885KMT2A 4578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.