SCHEMBL17387352

SCHEMBL17387352

C=[Hf](C)(C)(C)(CCC)(C1C=Cc2c(-c3cc(C)ccc3C)cccc21)C1C=Cc2c(-c3cc(C)ccc3C)cccc21

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA2 P47869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17387025 0.91 GABRG2 (0.30) GABRG2GABRB3GABRA2
SCHEMBL17386796 0.91
SCHEMBL17387281 0.88
SCHEMBL17387013 0.86
SCHEMBL17415917 0.86 GABRG2 (0.30) GABRG2GABRB3GABRA2
SCHEMBL17386991 0.86
SCHEMBL17386839 0.84
SCHEMBL17387154 0.84 CRHR1 (0.30)
SCHEMBL17387374 0.83
SCHEMBL17387221 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10005864-B2 Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORPORATION (JP) 2018-06-26 US disclosed
EP-3078670-B1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER JAPAN POLYETHYLENE CORP (JP) 2017-12-27 EP disclosed
US-20170320981-A1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER JAPAN POLYETHYLENE CORPORATION (JP) 2017-11-09 US disclosed
US-9783625-B2 Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORPORATION (JP) 2017-10-10 US disclosed
EP-3078670-A1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER Japan Polyethylene Corporation (JP) 2016-10-12 EP disclosed
US-20160009838-A1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER JAPAN POLYETHYLENE CORPORATION (JP) 2016-01-14 US disclosed
EP-2963045-A1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER Japan Polyethylene Corporation (JP) 2016-01-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170320981-A1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER CPNE4, PIN4, PIN1 GABRG2 4658/4885GABRB3 4779/4885GABRA2 4625/4885
US-20160009838-A1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER CPNE4, ALOX12, PIN1 GABRG2 4629/4885GABRB3 4836/4885GABRA2 4667/4885
US-10005864-B2 Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer CPNE4, PPOX, PIN1 GABRG2 4451/4885GABRB3 4657/4885GABRA2 4406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.