Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | F7 | P08709 | 3/20 | 0.51 |
| ▸ | F3 | P13726 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | FABP3 | P05413 | 2/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14759950 | 0.95 | MGLL (0.68) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL14759951 | 0.95 | MGLL (0.68) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL17401260 | 0.92 | ALDH1A1 (0.64) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL27059628 | 0.92 | MGLL (0.68) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL20714679 | 0.92 | MGLL (0.68) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL17298643 | 0.91 | MGLL (0.63) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL5868436 | 0.91 | DNM1 (0.69) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL5868433 | 0.91 | DNM1 (0.69) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL19695716 | 0.90 | MGLL (0.64) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL17401269 | 0.89 | DNM1 (0.62) | MGLLALDH1A1MAPTTHRBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840479-B2 | Polyamine-fatty acid derived lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-12-12 | — | — | US | disclosed |
| US-9840479-B2 | Polyamine-fatty acid derived lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-12-12 | — | — | US | disclosed |
| US-20160002178-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-07 | — | — | US | disclosed |
| US-20160002178-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002178-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | SGMS2, SGMS1, ARG2 | MGLL 129/4885ALDH1A1 2532/4885MAPT 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.