Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 8/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | PNLIP | P16233 | 1/20 | 0.35 |
| ▸ | SOD1 | P00441 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.32 |
| ▸ | BCL9 | O00512 | 2/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19559008 | 0.76 | KARS1 (0.31) | KARS1 | |
| SCHEMBL16006731 | 0.74 | CYP19A1 (0.60) | KARS1CYP19A1USP2MEN1KMT2A | |
| SCHEMBL16006739 | 0.73 | CYP19A1 (0.31) | CYP19A1 | |
| Ferruginol SCHEMBL155580 | 0.69 | KARS1 (0.73) | KARS1CYP19A1USP2MEN1KMT2A | |
| Ferruginol SCHEMBL13423521 | 0.69 | KARS1 (0.73) | KARS1CYP19A1USP2MEN1KMT2A | |
| Ferruginol SCHEMBL5315022 | 0.69 | KARS1 (0.73) | KARS1CYP19A1USP2MEN1KMT2A | |
| Sempervirol SCHEMBL10524412 | 0.66 | KARS1 (0.66) | KARS1CYP19A1USP2MEN1KMT2A | |
| Sempervirol SCHEMBL29495146 | 0.66 | KARS1 (0.66) | KARS1CYP19A1USP2MEN1KMT2A | |
| Sempervirol SCHEMBL10524413 | 0.66 | KARS1 (0.66) | KARS1CYP19A1USP2MEN1KMT2A | |
| Sugiol SCHEMBL28605319 | 0.63 | SOD1 (0.58) | KARS1CYP19A1USP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464963-B2 | Compounds from invasive Salvinias and methods of using the same | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2019-11-05 | — | — | US | disclosed |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2018-03-01 | — | — | US | disclosed |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2018-03-01 | — | — | US | disclosed |
| US-9809615-B2 | Anti-cancer compounds from invasive salvinias and methods of treating cancer | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2017-11-07 | — | — | US | disclosed |
| US-9809615-B2 | Anti-cancer compounds from invasive salvinias and methods of treating cancer | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2017-11-07 | — | — | US | disclosed |
| US-20160002279-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2016-01-07 | — | — | US | disclosed |
| US-20160002279-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464963-B2 | Compounds from invasive Salvinias and methods of using the same | MMP8, GUSB, MMP9 | KARS1 2969/4885CYP19A1 741/4885USP2 3495/4885 |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | MMP8, GUSB, MMP9 | KARS1 2969/4885CYP19A1 741/4885USP2 3495/4885 |
| US-20160002279-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | MMP8, GUSB, MMP9 | KARS1 2969/4885CYP19A1 741/4885USP2 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.