SCHEMBL1740705

SCHEMBL1740705

CCc1cc(OC)c(C[C@@H](C)N)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 1.00
HTR2A P28223 6/20 0.79
HTR1A P08908 2/20 0.69
HTR2C P28335 2/20 0.69
HTR2B P41595 2/20 0.69
CYP1A2 P05177 1/20 0.69
CYP3A4 P08684 1/20 0.69
CYP2D6 P10635 1/20 0.69
TSHR P16473 1/20 0.69
NFKB1 P19838 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1740704 1.00 TAAR1 (1.00) TAAR1HTR2AHTR1AHTR2CHTR2B
Hydrochloric Acid SCHEMBL29844954 0.98 TAAR1 (0.96) TAAR1HTR2AHTR1AHTR2CHTR2B
Isobutyraldehyde SCHEMBL11883853 0.92 TAAR1 (0.84) TAAR1HTR2AHTR1AHTR2CHTR2B
SCHEMBL29425260 0.88 HTR2A (1.00) TAAR1HTR2AHTR1AHTR2CHTR2B
SCHEMBL398581 0.88 HTR2A (1.00) TAAR1HTR2AHTR1AHTR2CHTR2B
SCHEMBL398580 0.88 HTR2A (1.00) TAAR1HTR2AHTR1AHTR2CHTR2B
SCHEMBL5308097 0.86 HTR2A (0.81) TAAR1HTR2AHTR1AHTR2CHTR2B
SCHEMBL5308098 0.86 HTR2A (0.81) TAAR1HTR2AHTR1AHTR2CHTR2B
Hydrochloric Acid SCHEMBL30341559 0.86 HTR2A (0.96) TAAR1HTR2AHTR1AHTR2CHTR2B
SCHEMBL5480637 0.85 TAAR1 (0.73) TAAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4499109-A1 PSYCHEDELIC COMPOSITIONS AND METHODS FOR FORMING THE SAME Ojai Energetics PBC (US) 2025-02-05 EP claimed
US-20240390301-A1 COMBINATIONS OF PERIPHERAL 5-HT2A RECEPTOR ANTAGONISTS AND CENTRAL 5-HT2A RECEPTOR AGONISTS GILGAMESH PHARMACEUTICALS, INC. (US) 2024-11-28 US claimed
WO-2024191924-A2 COMPOSITIONS AND METHODS OF USE THEREOF BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2024-09-19 WO claimed
US-20240285613-A1 TREATMENT FOR AUTOIMMUNE DISEASES LDN Pharma Limited (GB) 2024-08-29 US claimed
US-20240216339-A1 METHODS OF TREATING NEUROPSYCHIATRIC DISORDERS GILGAMESH PHARMACEUTICALS, INC. (US) 2024-07-04 US claimed
WO-2024102458-A1 METHODS OF USING TRAZODONE TO REVERSE THE EFFECTS OF 5-HT2A RECEPTOR AGONISTS GILGAMESH PHARMACEUTICALS, INC. (US) 2024-05-16 WO claimed
WO-2023183618-A1 PSYCHEDELIC COMPOSITIONS AND METHODS FOR FORMING THE SAME OJAI ENERGETICS PBC (US) 2023-09-28 WO claimed
WO-2023028086-A1 COMBINATIONS OF PERIPHERAL 5-HT2A RECEPTOR ANTAGONISTS AND CENTRAL 5-HT2A RECEPTOR AGONISTS GILGAMESH PHARMACEUTICALS, INC. (US) 2023-03-02 WO claimed
WO-2022261263-A1 METHODS OF TREATING NEUROPSYCHIATRIC DISORDERS GILGAMESH PHARMACEUTICALS, INC. (US) 2022-12-15 WO claimed
EP-4720030-A1 ASYMMETRIC PHENYLALKYLAMINES Alexander Shulgin Research Institute, Inc. (US) 2026-04-08 EP disclosed
US-20260060979-A1 METHOD FOR IMPROVING NEUROPLASTICITY ALTO NEUROSCIENCE INC (US) 2026-03-05 US disclosed
US-12534428-B2 Non-distillative process for manufacturing high purity amphetamines Pharmapotheca A, Inc. (US) 2026-01-27 US disclosed
EP-4673127-A1 DEUTERATED AND FLUORINATED EMPATHOGENS Alexander Shulgin Research Institute, Inc. (US) 2026-01-07 EP disclosed
EP-4673430-A2 PHENYLALKYLAMINE PRODRUGS Alexander Shulgin Research Institute, Inc. (US) 2026-01-07 EP disclosed
US-20080075772-A1 PHARMACEUTICAL COMPOSITIONS HAVING NOVEL SCORING PATTERNS AND METHODS OF USING THOSE COMPOSITIONS ACCU-BREAK TECHNOLOGIES, INC. 2008-03-27 US disclosed
EP-1868593-A2 IMPROVED METHODS OF AND COMPOSITIONS FOR THE PREVENTION OF ANXIETY, SUBSTANCE ABUSE, AND DEPENDENCE Hythiam, Inc. (US) 2007-12-26 EP disclosed
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-01 US disclosed
WO-2006110642-A2 IMPROVED METHODS OF AND COMPOSITIONS FOR THE PREVENTION OF ANXIETY, SUBSTANCE ABUSE, AND DEPENDENCE HYTHIAM, INC. (US) 2006-10-19 WO disclosed
US-6472227-B1 A FLUORESCEIN MOIETY IS INCLUDED IN THE TRACER, WHILE A POLY(AMINO ACID) FORMS A PART OF THE IMMUNOGEN FOR DETERMINING THE AMOUNT OF BARBITURATE IN FLUIDS, ESPECIALLY BIOLOGICAL FLUIDS SUCH AS SERUM, PLASMA OR URINE ABBOTT LABORATORIES 2002-10-29 US disclosed
US-4000197-A FROM PHENYLACETONES AND METHYL BENZYLAMINE, REDUCTION, HYDROGENOLYSIS THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1976-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240390301-A1 COMBINATIONS OF PERIPHERAL 5-HT2A RECEPTOR ANTAGONISTS AND CENTRAL 5-HT2A RECEPTOR AGONISTS HTR2A, HTR2C, HTR5A TAAR1 77/4885HTR2A 1/4885HTR1A 4/4885
US-20070027208-A1 Antiparkinsonian Action of Phenylisopropylamines PNMT, SNCA, COMT TAAR1 1075/4885HTR2A 18/4885HTR1A 29/4885
US-12534428-B2 Non-distillative process for manufacturing high purity amphetamines SMS, SRMS, SRM TAAR1 28/4885HTR2A 118/4885HTR1A 84/4885
US-20260060979-A1 METHOD FOR IMPROVING NEUROPLASTICITY NTRK2, BDNF, GRIN2A TAAR1 128/4885HTR2A 13/4885HTR1A 38/4885
US-20240216339-A1 METHODS OF TREATING NEUROPSYCHIATRIC DISORDERS HCRTR2, HCRTR1, HTR2A TAAR1 73/4885HTR2A 3/4885HTR1A 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.