SCHEMBL4151490

SCHEMBL4151490

CCNC(=O)c1ccc(C)cc1

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.63
POLB P06746 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.62
ALDH1A1 P00352 4/20 0.61
GAA P10253 1/20 0.61
HDAC1 Q13547 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
NPC1 O15118 5/20 0.56
RAB9A P51151 4/20 0.56
KMT2A Q03164 1/20 0.56
TDP1 Q9NUW8 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
MMP13 P45452 1/20 0.54
MAPT P10636 1/20 0.53
KDM4E B2RXH2 1/20 0.53
HTT P42858 1/20 0.53
NPSR1 Q6W5P4 1/20 0.51
CA12 O43570 1/20 0.51
CA9 Q16790 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5614038 0.98 LMNA (0.61) LMNAPOLBL3MBTL1ALDH1A1GAA
SCHEMBL5909057 0.91 CA12 (0.58) LMNAPOLBL3MBTL1ALDH1A1GAA
SCHEMBL11220601 0.84 LMNA (0.85) LMNAPOLBL3MBTL1ALDH1A1GAA
SCHEMBL765958 0.83 L3MBTL1 (0.74) LMNAPOLBL3MBTL1ALDH1A1GAA
SCHEMBL12065463 0.83 ALDH1A1 (0.68) LMNAPOLBL3MBTL1ALDH1A1GAA
SCHEMBL10872851 0.83 LMNA (0.69) LMNAPOLBL3MBTL1ALDH1A1GAA
SCHEMBL10604141 0.83 LMNA (0.63) LMNAPOLBL3MBTL1ALDH1A1GAA
SCHEMBL8158111 0.83 NR1H4 (0.54) LMNAPOLBALDH1A1GAAHDAC1
SCHEMBL9625469 0.83 MPO (0.59) LMNAL3MBTL1ALDH1A1KMT2AMAPT
SCHEMBL13702393 0.83 PLK1 (0.66) LMNAALDH1A1HDAC6KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1433296-A Nail enamel composition containing urea-modified thixotropic agent OREAL (FR) 2003-07-30 CN claimed
EP-0287421-B1 PROCESS FOR THE CYCLIC PRODUCTION OF HYDROGEN PEROXIDE ELF ATOCHEM S.A. (FR) 1991-06-05 EP claimed
US-4803063-A REDOX REACTION OF QUINONES IN AROMATIC AMIDE SOLVENT ATOCHEM (FR) 1989-02-07 US claimed
EP-0287421-A1 Process for the cyclic production of hydrogen peroxide ELF ATOCHEM S.A. (FR) 1988-10-19 EP claimed
US-20230357259-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2023-11-09 US disclosed
US-20230357259-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2023-11-09 US disclosed
EP-4227298-A1 SMALL MOLECULE COMPOUND SERVING AS JAK KINASE INHIBITOR AND USE THEREOF Technoderma Medicines Inc. (CN) 2023-08-16 EP disclosed
CN-116223598-A Electrochemical detection method of menthol based on competition with ferrocene for entering beta-cyclodextrin 东南大学 2023-06-06 CN disclosed
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-05-25 US disclosed
WO-2023016134-A1 COMPOUND CONTAINING TETRAHYDROPTERIN STRUCTURE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国药科大学 2023-02-16 WO disclosed
WO-2023011301-A1 JAK INHIBITOR WITH HIGH ORAL BIOAVAILABILITY 嘉兴特科罗生物科技有限公司 2023-02-09 WO disclosed
CN-115677696-A Preparation method of benzonaphthyridine derivative 华侨大学 2023-02-03 CN disclosed
US-4151351-A PROSTAGLANDINS, ANTIINFLAMMATORY THE UPJOHN COMPANY (US) 1979-04-24 US disclosed
US-4131738-A 6-Hydroxy-PGE1 compounds THE UPJOHN COMPANY (US) 1978-12-26 US disclosed
US-4128713-A 6,7-Didehydro-PGI1 compounds THE UPJOHN COMPANY (US) 1978-12-05 US disclosed
US-4126744-A PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS THE UPJOHN COMPANY (US) 1978-11-21 US disclosed
US-4112224-A PROSTAGLANDIN THE UPJOHN COMPANY (US) 1978-09-05 US disclosed
US-4109082-A PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS THE UPJOHN COMPANY (US) 1978-08-22 US disclosed
US-4100192-A Inter-phenylene-PG amides THE UPJOHN COMPANY (US) 1978-07-11 US disclosed
US-4097489-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF SSB, EBNA1BP2, PML LMNA 822/4885POLB 917/4885L3MBTL1 2434/4885
US-20230357259-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF DOCK11, PAICS, RHOA LMNA 1356/4885POLB 3905/4885L3MBTL1 4178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.