SCHEMBL17414848

SCHEMBL17414848

[SiH3]O[SiH2]c1cccc2c1-c1ccccc1-2

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
ATM Q13315 1/20 0.30
HSD17B10 Q99714 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2887405 0.77 MAOA (0.38) ALDH1A1TSHRMAPK1ATMHSD17B10
SCHEMBL11898469 0.75 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1ATMHSD17B10
SCHEMBL10820765 0.72 ALDH1A1 (0.38) ALDH1A1MAPK1HSD17B10
SCHEMBL2146499 0.68 CA1 (0.50) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL23071565 0.68 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1ATMHSD17B10
SCHEMBL29236876 0.68 ALDH1A1 (0.47) ALDH1A1TSHRMAPK1ATMHSD17B10
SCHEMBL170029 0.67 LMNA (0.41) ALDH1A1TSHRHSD17B10L3MBTL1
SCHEMBL5535898 0.67 CYP3A4 (0.41) ALDH1A1TSHRHSD17B10L3MBTL1
SCHEMBL9014022 0.67 TSHR (0.41) ALDH1A1TSHR
SCHEMBL43315 0.67 TSHR (0.41) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2966115-B1 TEMPERATURE-RESISTANT SILICONE RESINS BOEING CO (US) 2024-01-24 EP disclosed
US-10563017-B2 Temperature-resistant silicone resins THE BOEING COMPANY (US) 2020-02-18 US disclosed
US-10189953-B2 Temperature-resistant silicone resins THE BOEING COMPANY (US) 2019-01-29 US disclosed
US-9932475-B2 Temperature-resistant silicone resins THE BOEING COMPANY (US) 2018-04-03 US disclosed
US-20180072887-A1 TEMPERATURE-RESISTANT SILICONE RESINS THE BOEING COMPANY 2018-03-15 US disclosed
EP-3269756-A1 TEMPERATURE-RESISTANT SILICONE RESINS The Boeing Company (US) 2018-01-17 EP disclosed
EP-2966114-B1 TEMPERATURE-RESISTANT SILICONE RESINS BOEING CO (US) 2017-05-03 EP disclosed
US-20170101510-A1 TEMPERATURE-RESISTANT SILICONE RESINS THE BOEING COMPANY 2017-04-13 US disclosed
US-9534089-B2 Temperature-resistant silicone resins THE BOEING COMPANY (US) 2017-01-03 US disclosed
US-20160185919-A1 TEMPERATURE-RESISTANT SILICONE RESINS THE BOEING COMPANY 2016-06-30 US disclosed
US-9309359-B2 Temperature-resistant silicone resins THE BOEING COMPANY (US) 2016-04-12 US disclosed
US-20160009864-A1 TEMPERATURE-RESISTANT SILICONE RESINS THE BOEING COMPANY 2016-01-14 US disclosed
US-20160009867-A1 TEMPERATURE-RESISTANT SILICONE RESINS THE BOEING COMPANY 2016-01-14 US disclosed
EP-2966115-A2 TEMPERATURE-RESISTANT SILICONE RESINS The Boeing Company (US) 2016-01-13 EP disclosed
EP-2966114-A1 TEMPERATURE-RESISTANT SILICONE RESINS The Boeing Company (US) 2016-01-13 EP disclosed