Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | RECQL | P46063 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170029 | 0.78 | LMNA (0.41) | MAPTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL17414848 | 0.77 | ALDH1A1 (0.30) | ALDH1A1HSD17B10MAPK1TSHRATM | |
| SCHEMBL29837181 | 0.73 | MAOA (0.56) | MAOAMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL2729251 | 0.73 | MAOA (0.56) | MAOAMAPTALDH1A1HPGDHSD17B10 | |
| Phenol SCHEMBL4232150 | 0.72 | CA2 (0.44) | MAPTALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL9810885 | 0.70 | MAOA (0.48) | MAOAMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL29455667 | 0.69 | MAOA (0.52) | MAOAMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL29469517 | 0.69 | MAOA (0.52) | MAOAMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL31534010 | 0.68 | MAOA (0.50) | MAOAMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL31623901 | 0.68 | MAOA (0.50) | MAOAMAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536282-B2 | Silylated polycarbonate polymers, method of making, and articles | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-7678864-B2 | Silylated polycarbonate polymers, method of making, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-03-16 | — | — | US | disclosed |
| US-20090326181-A1 | Silylated polycarbonate polymers, method of making, and articles | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-12-31 | — | — | US | disclosed |
| EP-2104698-A1 | MONOMERS FOR THE PREPARATION OF SILYLATED POLYCARBONATE POLYMERS | Momentive Performance Materials Inc. (US) | 2009-09-30 | — | — | EP | disclosed |
| US-20080306294-A1 | Silylated polycarbonate polymers, method of making, and articles | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-12-11 | — | — | US | disclosed |
| WO-2008079447-A1 | SILYLATED POLYCARBONATE POLYMERS, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008079358-A1 | MONOMERS FOR THE PREPARATION OF SILYLATED POLYCARBONATE POLYMERS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-07-03 | — | — | WO | disclosed |
| US-20080153994-A1 | SILYLATED POLYCARBONATE POLYMERS, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326181-A1 | Silylated polycarbonate polymers, method of making, and articles | ZRANB2, CYP8B1, ZYX | MAOA 993/4885MAPT 3966/4885ALDH1A1 1441/4885 |
| US-20080306294-A1 | Silylated polycarbonate polymers, method of making, and articles | ZRANB2, ZYX, GLB1 | MAOA 805/4885MAPT 4148/4885ALDH1A1 1705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.