SCHEMBL170029

SCHEMBL170029

Oc1ccccc1[SiH2]O[SiH3]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.41
ALDH1A1 P00352 5/20 0.41
CA2 P00918 4/20 0.41
ALOX15 P16050 3/20 0.41
MAPT P10636 3/20 0.41
HPGD P15428 3/20 0.41
HSD17B10 Q99714 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
KDM4E B2RXH2 2/20 0.41
NPC1 O15118 2/20 0.41
CA4 P22748 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
EGFR P00533 2/20 0.41
FYN P06241 2/20 0.41
MMP9 P14780 2/20 0.41
RECQL P46063 2/20 0.41
CA12 O43570 1/20 0.41
GMNN O75496 1/20 0.41
POLB P06746 1/20 0.41
CA3 P07451 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL4232150 0.92 CA2 (0.44) LMNAALDH1A1CA2ALOX15MAPT
SCHEMBL9775497 0.80 LMNA (0.45) LMNAALDH1A1CA2ALOX15MAPT
SCHEMBL2887405 0.78 MAOA (0.38) LMNAALDH1A1CA2ALOX15MAPT
SCHEMBL2420083 0.73 CA2 (0.46) LMNAALDH1A1CA2ALOX15MAPT
SCHEMBL5535898 0.71 CYP3A4 (0.41) ALDH1A1ALOX15MAPTHPGDHSD17B10
SCHEMBL9014022 0.71 TSHR (0.41) LMNAALDH1A1TSHRIDO1CYP1A2
SCHEMBL43315 0.71 TSHR (0.41) ALDH1A1CA2TDP1NPC1SMN1; SMN2
SCHEMBL5815900 0.71 APOBEC3G (0.39) LMNAHPGDL3MBTL1TSHRGAA
SCHEMBL1420028 0.71 ALDH1A1 (0.36) LMNAALDH1A1CA2ALOX15MAPT
SCHEMBL19809449 0.71 ALDH1A1 (0.53) LMNAALDH1A1CA2ALOX15MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110038938-A1 Compositions for tissue augmentation DERMAL TECHNOLOGIES, LLC 2011-02-17 US claimed
EP-2254610-A2 COMPOSITIONS FOR TISSUE AUGMENTATION Dermal Technologies, Llc (US) 2010-12-01 EP claimed
CN-100551948-C Transparent and high heat polycarbonate-polysiloxane copolymers and transparent blends containing polycarbonate and processes for making same GEN ELECTRIC (NL) 2009-10-21 CN claimed
WO-2009105614-A2 COMPOSITIONS FOR TISSUE AUGMENTATION DERMAL TECHNOLOGIES, LLC (US) 2009-08-27 WO claimed
US-7232865-B2 Transparent and high-heat polycarbonate-polysiloxane copolymers and transparent blends with polycarbonate and a process for preparing same GENERAL ELECTRIC COMPANY (US) 2007-06-19 US claimed
CN-1798791-A Transparent and high heat polycarbonate-polysiloxane copolymers and transparent blends containing polycarbonate and processes for making same GEN ELECTRIC (US) 2006-07-05 CN claimed
EP-1611176-A2 TRANSPARENT AND HIGH-HEAT POLYCARBONATE-POLYSILOXANE COPOLYMERS AND TRANSPARENT BLENDS WITH POLYCARBONATE AND A PROCESS FOR PREPARING SAME GENERAL ELECTRIC COMPANY (US) 2006-01-04 EP claimed
US-20040220330-A1 Transparent and high-heat polycarbonate-polysiloxane copolymers and transparent blends with polycarbonate and a process for preparing same SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2004-11-04 US claimed
WO-2004076512-A2 TRANSPARENT AND HIGH-HEAT POLYCARBONATE-POLYSILOXANE COPOLYMERS AND TRANSPARENT BLENDS WITH POLYCARBONATE AND A PROCESS FOR PREPARING SAME GENERAL ELECTRIC COMPANY (US) 2004-09-10 WO claimed
EP-0433746-B1 Thermoplastic flame retardant silicone polyphenylene ether graft copolymers GEN ELECTRIC (US) 1995-03-22 EP claimed
US-5281686-A Oxidative coupling 2,6-dialkylphenol to monophenol substituted polysiloxane GENERAL ELECTRIC COMPANY (US) 1994-01-25 US claimed
US-5204438-A Silicone macromers and thermoplastic flame retardant silicone-polyphenylene ether graft copolymers obtained therefrom GENERAL ELECTRIC COMPANY (US) 1993-04-20 US claimed
EP-0515196-A2 Method for making silicone polyphenylene ether graft copolymers and products GENERAL ELECTRIC COMPANY (US) 1992-11-25 EP claimed
EP-0433746-A2 Thermoplastic flame retardant silicone polyphenylene ether graft copolymers GENERAL ELECTRIC COMPANY (US) 1991-06-26 EP claimed
JP-4120132-A None JP disclosed
US-20240318032-A1 Insulation System for Electrically Rotating MachinesAnd Method for the Production Thereof SIEMENS AKTIENGESELLSCHAFT (DE) 2024-09-26 US disclosed
EP-2691476-B1 AIRCRAFT COMPONENT COMPRISING FLAME RETARDANT SILOXANE-CONTAINING POLYMER COMPOSITIONS SHPP GLOBAL TECH BV (NL) 2021-04-21 EP disclosed
US-5025074-A Flame retardant organopolysiloxane-polycarbonate triblock copolymers GENERAL ELECTRIC COMPANY (US) 1991-06-18 US disclosed
US-4895766-A Release agent which is blend of silicones and polysiloxanes GENERAL ELECTRIC COMPANY (US) 1990-01-23 US disclosed
EP-0334190-A2 Improved bakeware coating GENERAL ELECTRIC COMPANY (US) 1989-09-27 EP disclosed